Evaluation of p300 and spectral resolution in children with attention deficit hyperactivity disorder and specific learning disorder

Seçen Yazıcı, Meryem; Serdengeçti, Nihal; Dikmen, Merve; Koyuncu, Zehra; Sandıkçı, Beyza; Arslan, Büşra; Acar, Melda; Kara, Eyyup; Tarakçıoğlu, Mahmut Cem; Kadak, Muhammed Tayyib

doi:10.1016/j.pscychresns.2023.111688

Cited by 3 publications

(1 citation statement)

References 63 publications

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“…The current diagnostic process for ADHD within the clinical setting primarily relies on a subjective interview and standardized rating scales ( 4 , 5 ). Although P300 event-related potentials are promising electroencephalography signatures that can objectively discriminate individuals with ADHD, it is not formally used for screening or diagnostic purposes due to its need for sophisticated equipment ( 6 , 7 ). Other physiological differences have been reported on the markers within the heart–brain and gut–brain axes as well as motor cortex physiology; however, these remain correlative measures and are unable to provide diagnostic confirmation ( 8 , 9 ).…”

Section: Introductionmentioning

confidence: 99%

Utilizing artificial intelligence-based eye tracking technology for screening ADHD symptoms in children

Chen,

Wang,

Yang

et al. 2023

Front. Psychiatry

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ObjectiveTo explore the potential of using artificial intelligence (AI)-based eye tracking technology on a tablet for screening Attention-deficit/hyperactivity disorder (ADHD) symptoms in children.MethodsWe recruited 112 children diagnosed with ADHD (ADHD group; mean age: 9.40 ± 1.70 years old) and 325 typically developing children (TD group; mean age: 9.45 ± 1.59 years old). We designed a data-driven end-to-end convolutional neural network appearance-based model to predict eye gaze to permit eye-tracking under low resolution and sampling rates. The participants then completed the eye tracking task on a tablet, which consisted of a simple fixation task as well as 14 prosaccade (looking toward target) and 14 antisaccade (looking away from target) trials, measuring attention and inhibition, respectively.ResultsTwo-way MANOVA analyses demonstrated that diagnosis and age had significant effects on performance on the fixation task [diagnosis: F(2, 432) = 8.231, ***p < 0.001; Wilks’ Λ = 0.963; age: F(2, 432) = 3.999, *p < 0.019; Wilks’ Λ = 0.982], prosaccade task [age: F(16, 418) = 3.847, ***p < 0.001; Wilks’ Λ = 0.872], and antisaccade task [diagnosis: F(16, 418) = 1.738, *p = 0.038; Wilks’ Λ = 0.938; age: F(16, 418) = 4.508, ***p < 0.001; Wilks’ Λ = 0.853]. Correlational analyses revealed that participants with higher SNAP-IV score were more likely to have shorter fixation duration and more fixation intervals (r = −0.160, 95% CI [0.250, 0.067], ***p < 0.001), poorer scores on adjusted prosaccade accuracy, and poorer scores on antisaccade accuracy (Accuracy: r = −0.105, 95% CI [−0.197, −0.011], *p = 0.029; Adjusted accuracy: r = −0.108, 95% CI [−0.200, −0.015], *p = 0.024).ConclusionOur AI-based eye tracking technology implemented on a tablet could reliably discriminate eye movements of the TD group and the ADHD group, providing a potential solution for ADHD screening outside of clinical settings.

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Section: Introductionmentioning

confidence: 99%

Utilizing artificial intelligence-based eye tracking technology for screening ADHD symptoms in children

Chen,

Wang,

Yang

et al. 2023

Front. Psychiatry

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Neural Oscillation Features of ADHD Symptoms in Children: EEG Evidence from Resting State and Oddball Task

Zhang,

Yu,

Cui

et al. 2024

Preprint

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The current study examined resting-state and event-related neural oscillations associated with ADHD symptoms in children aged 6-12. 77 children were assessed using the Integrated Visual and Auditory Continuous Performance Test (IVA-CPT) and EEG during resting-state. A group of these children also completed a classic visual oddball task. Key findings include increased relative delta activity at left parietal electrodes during eyes-open and decreased relative theta activity at left posterior electrodes during eyes-closed, both associated with poor attention. Increased beta activity at right parieto-occipital electrodes during eyes-open and increased alpha activity at bilateral posterior electrodes during eyes-closed were associated with poor response control. In addition, the power of the P3 component was negatively correlated with attention across most frequency bands and conditions, except for delta power in the standard condition. Furthermore, combining multiple metrics, especially resting-state EEG oscillations, event-related oscillations, and parental ratings, provided a more robust prediction. The current study identified important brain regions and frequency bands related to ADHD symptoms, offering new insights for multi-metric prediction and clinical guidance.

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Effects of Transcranial Direct Current Stimulation on Potential P300-Related Events and Alpha and Beta EEG Band Rhythms in Parkinson's Disease

Fabio,

Suriano,

Gangemi

2024

J. Integr. Neurosci.

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Background: Parkinson’s disease is one of the most common neurodegenerative disorders. While a definitive cure for Parkinson’s disease remains elusive, a range of treatments are available to slow its progression and counteract its symptoms. Transcranial direct current stimulation (tDCS) represents a non-invasive method to induce brain plasticity. The aim of this study was to examine the effects of two weeks of tDCS on the left dorsolateral prefrontal cortex (DLPFC) on the neurophysiological functioning of Parkinson’s patients. Methods: Thirty patients aged between 67 and 82 years with Parkinson’s disease participated to the experiment. Fifteen underwent tDCS on the left DLPFC, while fifteen underwent sham tDCS. Neurophysiological functions were assessed before and after tDCS using electroencephalogram methods for alpha and beta band rhythms and P300 event-related potential latency. Results: tDCS led to a reduction in the onset latency of the P300 response and an increase in the power spectrum of the alpha and beta band rhythms. Conclusions: This research enhances our understanding of the potential effects of tDCS in the context of Parkinson’s disease treatment, as the reduction in P300 latency and the increase in alpha and beta bands are associated with improvements in cognitive aspects.

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Evaluation of p300 and spectral resolution in children with attention deficit hyperactivity disorder and specific learning disorder

Cited by 3 publications

References 63 publications

Utilizing artificial intelligence-based eye tracking technology for screening ADHD symptoms in children

Utilizing artificial intelligence-based eye tracking technology for screening ADHD symptoms in children

Neural Oscillation Features of ADHD Symptoms in Children: EEG Evidence from Resting State and Oddball Task

Effects of Transcranial Direct Current Stimulation on Potential P300-Related Events and Alpha and Beta EEG Band Rhythms in Parkinson's Disease

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