Evaluation of Pain Regression in Patients with Temporomandibular Dysfunction Treated by Intra-Articular Platelet-Rich Plasma Injections: A Preliminary Report

Abstract

Objective. The objective of this study was to evaluate the regression of temporomandibular pain as a result of intra-articular injections of platelet-rich plasma (PRP) to patients with temporomandibular joint dysfunction previously subjected to prosthetic treatment. Materials and Methods. The baseline study material consisted of 10 patients, both males and females, aged 28 to 53 years, previously treated due to painful temporomandibular joint dysfunction using occlusal splints. All patients were carried out to a specialist functional assessment of the dysfunction using the Polish version of the RDC/TMD questionnaire axis I and II. Intra-articular injections were preceded by a preparation of PRP. The injection sites were determined by the method used during arthroscopic surgical procedures. Following aspiration, 0.5 mL of plasma was injected into each temporomandibular joint. Results. The comparison of the intensity of pain during all examinations suggests a beneficial effect of the procedure being performed as the mean VAS score was 6.5 at examination I, 2.8 at examination II, and 0.6 at examination III. Conclusion. Application of the intra-articular injections of platelet-rich plasma into the temporomandibular joints has a positive impact on the reduction of the intensity of pain experienced by patients treated for temporomandibular joint dysfunction.

Bilateral platelet rich plasma injections with assisted techniques for temporomandibular joint disorders

“…However, differences in application techniques, application regions, and PRP compositions make comparisons of efficacy results difficult. Potential complications following the procedures are mild; therefore, this method of treatment appears to be safer in comparision with surgical techniques [4]. PRP injection applied by orthopaedic surgeons and sport medicine physicians to the knee, ankle, and elbow joints [11,12].…”

“…PRP injection applied by orthopaedic surgeons and sport medicine physicians to the knee, ankle, and elbow joints [11,12]. New studies suggest that PRP injection might be beneficial for TMJ ligament and cartilage healing [4].…”

“…Under sedative anaesthesia, three ml injections (2 ml into the joint capsule and 1 ml into the pericapsular region) were applied to both sides [4] (Figure 2). After PRP injection, patients' jaws were immobilized with an elastic bandage for three days during which just liquid Three months after the last injection, patients were asked to complete a questionnaire.…”

Temporomandi̇bular Eklem Osteoartri̇tli̇ Hastalarda Artrosentezi̇ Taki̇ben Yapilan Trombosi̇tten Zengi̇n Plazma, Hyaluroni̇k Asi̇t Ve Korti̇kosteroi̇d Enjeksi̇yonlarinin Temporomandi̇bular Eklem Palpasyonunda Oluşan Ağriya Etki̇leri̇ni̇n Karşilaştirilmasi

“…6,25 TME hastalıklarının tedavisinde PRP'nin kulanı-mını içeren çalışma sonuçları, bizim çalışma sonuç-larımız ile genel olarak uyumludur.Pihut ve ark. 15 ve…”

“…6,[15][16][17] Bu son dönem yapılan çalışmalarda PRP nin daha iyi klinik ve radyolojik iyileşme sağladığı ve ayrıca eklem sesi ve ağrılarda azalmanın yanı sıra ağız açma miktarlarındada artış sağladığı belirlilmiştir. 6,[15][16][17] Son dönem yapılan bir çalışmada Hegap ve ark.…”