Evaluation of paravertebral muscle atrophy and fatty degeneration in ankylosing spondylitis

Reşorlu, Hatice; Savaş, Yılmaz; Aylanç, Nilüfer; Gökmen, Ferhat

doi:10.1080/14397595.2016.1245176

Cited by 24 publications

(34 citation statements)

References 18 publications

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“…Another important finding from the same study was the significant fat degeneration at L3-4 levels in all patients with sacroiliitis. Similar results were shown by Resorlu et al [12].…”

Section: Discussionsupporting

confidence: 92%

Оценка На Атрофията И Мастната Дегенерация На Паравертебралната Мускулатура При Аксиален Спондилоартрит

Teneva

Georgiev

2020

BRJ

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ВЪВЕДЕНИЕ Саркопения или още мускулна атрофия е общ белег на множество хронично протичащи заболявания на мускулно-скелетната система, включително и състояния, придружени от болка в поясно-кръсцовия отдел. ЦЕЛ Целта на проучването е да се оценят морфологичните промени на мускулите в лумбо-сакралната област при пациенти с аксиален спондилоартрит, преминали магнитно-резонансна томография, и да се сравнят с група пациенти също с хронична болка с кръста, но с друга етиология. МЕТОДИ Ретроспективното проучване обхваща 82 пациенти, разделени в три групи на интерес - първа група- контроли с лумбосакрална болка, втора група – пациенти с нерентгенографски аксиален спондилоартит (nr-AxSpA) и трета група – с анкилозиращ спондилит (АС). При всички болни е проведена рентгенография и магнитно-резонансна томография на сакроилиачните стави. Измерена е площта (area) на следните паравертебралните мускул: m. multifidus, m. erector spinae и m. psoas. Наличната мастна инфилтрация на мускулите бе оценена според скала от 0 до 4. РЕЗУЛТАТИ Площта на изследваните параспинални мускулни групи не се различава сигнификантно между изследваните три групи (p > .05). Въпреки това те се различават сигнификантно по мастната инфилтрация на m. multifidus (p = .02), като 15/23 (65%) от пациентите с анкилозиращ спондилит имат висока степен на мастна дегенерация (оценка ≥ 3) в сравнение с 27.5% и 21% съответно в първа и втора група. Множествен линеен регресионен анализ определи, че възрастта и C-реактивен протеин са независими предиктори за площта на m. multifidus (p < .001). ЗАКЛЮЧЕНИЕ Образните характеристики на m. multifidus може да са полезна величина за оценка на болни с аксиален спондилоартрит. Възпалението може да играе ключова роля за саркопенията на m. multifidus при пациенти с хронична болка в кръста. Неговата мастна инфилтрация се асоциира с рентгенографските промени и може да отграничи пациенти с анкилозиращ спондилит от такива с нерентгенографски аксиален спондилоартрит и лумбосакрална болка с друг произход.

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“…Another important finding from the same study was the significant fat degeneration at L3-4 levels in all patients with sacroiliitis. Similar results were shown by Resorlu et al [12].…”

Section: Discussionsupporting

confidence: 92%

Оценка На Атрофията И Мастната Дегенерация На Паравертебралната Мускулатура При Аксиален Спондилоартрит

Teneva

Georgiev

2020

BRJ

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“…Although axSpa is a systemic disease, the initial inflammatory changes occur in the lumbo-pelvic region, and the lumbar paraspinal muscles are therefore a target for any primary or secondary pathological changes. Studies using MRI have demonstrated decreased CSA of the multifidus muscles, as well as changes in composition of the muscles (Akgul et al, 2013; Resorlu et al, 2017). Although exercise is beneficial in diseases such as axSpa, the mechanisms are not known.…”

Section: Changes In Trunk Muscles Associated With Low Back Pain and Smentioning

confidence: 99%

State-of-the-Art Exercise Concepts for Lumbopelvic and Spinal Muscles – Transferability to Microgravity

2019

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Low back pain (LBP) is the leading cause of disability worldwide. Over the last three decades, changes to key recommendations in clinical practice guidelines for management of LBP have placed greater emphasis on self-management and utilization of exercise programs targeting improvements in function. Recommendations have also suggested that physical treatments for persistent LBP should be tailored to the individual. This mini review will draw parallels between changes, which occur to the neuromuscular system in microgravity and conditions such as LBP which occur on Earth. Prolonged exposure to microgravity is associated with both LBP and muscle atrophy of the intrinsic muscles of the spine, including the lumbar multifidus. The finding of atrophy of spinal muscles has also commonly been reported in terrestrial LBP sufferers. Studying astronauts provides a unique perspective and valuable model for testing the effectiveness of exercise interventions, which have been developed on Earth. One such approach is motor control training, which is a broad term that can include all the sensory and motor aspects of spinal motor function. There is evidence to support the use of this exercise approach, but unlike changes seen in muscles of LBP sufferers on Earth, the changes induced by exposure to microgravity are rapid, and are relatively consistent in nature. Drawing parallels between changes which occur to the neuromuscular system in the absence of gravity and which exercises best restore size and function could help health professionals tailor improved interventions for terrestrial populations.

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“…Paravertebral muscles, transversus abdominis, external oblique, internal oblique muscles forming the core have been shown to be active during endurance tests 22,23 . It is stated in some rheumatoid diseases that atrophy can be seen in these muscles and this atrophy may cause decrease in strength and endurance test scores 24 . However, we did not find any study examining the presence of atrophy in the trunk muscles or evaluating the trunk muscle morphology (ultrasound imaging), strength and endurance of SSc patients.…”

Section: Discussionmentioning

confidence: 99%

Association between core stability and physical function, functional performance in patients with systemic sclerosis

2021

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Objective To investigate the association of core stability with physical function and functional performance in patients with systemic sclerosis (SSc). Methods Forty patients who met the American College of Rheumatology / European League Against Rheumatism 2013 classification criteria for SSc were included in the cross‐sectional study. For evaluation of core stability, trunk muscle endurance and trunk muscle strength were assessed. Trunk extensor and trunk flexor endurance tests were used for assessment of trunk muscle endurance. Trunk muscle strength was measured with a hand‐held dynamometer and modified sit‐up test. To measure physical function the Health Assessment Questionnaire Disability Index (HAQ‐DI) and to measure functional performance 6‐minute walking test (6MWT) and sit‐to‐stand test (STS) were used. Results Patients with SSc had lower mean trunk extensor and flexor endurance test times (49.87 ± 30.81 and 32.17 ± 15.42 seconds, respectively), modified sit‐up test repetition (17.42 ± 7.81) and trunk extensor and flexor muscle strength (7.48 ± 2.29 kg and 6.20 ± 1.68 kg, respectively) when compared to the reference values in healthy individuals. All measurements were used to evaluate core stability associated with HAQ‐DI score, 6DMWT walking distance and STS test duration (all P < .05). Conclusion Patients with SSc have markedly reduced core stability and this negatively affects the physical function and functional performance. Therefore, this study highlights the importance of trunk muscle in patients with SSc. We suggest that not only upper‐lower extremity muscles, but also trunk muscle strength and endurance should be measured and core stability exercises can be added to the training programs to maintain and/or improve physical functions and functional performance in SSc patients.

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Evaluation of paravertebral muscle atrophy and fatty degeneration in ankylosing spondylitis

Abstract: Chronic inflammation, cytokine-mediated fibrosis, immobilization, and postural changes in ankylosing spondylitis contribute to fatty degeneration and atrophy in the paravertebral muscles.

Cited by 24 publications

References 18 publications

Оценка На Атрофията И Мастната Дегенерация На Паравертебралната Мускулатура При Аксиален Спондилоартрит

Оценка На Атрофията И Мастната Дегенерация На Паравертебралната Мускулатура При Аксиален Спондилоартрит

State-of-the-Art Exercise Concepts for Lumbopelvic and Spinal Muscles – Transferability to Microgravity

Association between core stability and physical function, functional performance in patients with systemic sclerosis

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