Evaluation of phytochemical, antimicrobial and time-killing assay of Camellia species

Pradhan, Surbhi; Dubey, Ramesh Chandra

doi:10.1007/s42535-020-00153-2

Cited by 8 publications

(4 citation statements)

References 26 publications

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“…Phytochemical analysis of the tea extract revealed the content of alkaloids, flavonoids, carbohydrates, saponins, tannins, steroids, terpenoids and cardiac glycosides. 20 Similar results were obtained by Shixia et al 21 They found that quinoa (Chenopodium quinoa Willd.) saponins caused severe damage to S. aureus, S. epidermidis, B. cereus, S. enteritidis, P. aeruginosa, and L. ivanovii through cell wall degradation with subsequent disruption of the cytoplasmic membrane and membrane proteins, leading to leakage cell contents.…”

Section: Edible Plantssupporting

confidence: 78%

Antimicrobial activity of saponin-containing plants: review

Alina,

Kiełb Ewa,

František

2023

JDVAR

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The resistance of pathogenic microorganisms to antibiotics has become a "scourge" of the medical field in recent decades. In this regard, the vector of medical research rightly changed in favor of the search for natural mechanisms to fight pathogens. Nature has produced mechanisms for maintaining balance for millions of years, so it is reasonable to investigate and, in the future, use such mechanisms. This current study reviews and analyzes the last five years of research on the effects of saponin-containing plants on the most common pathogens. The analysis of literary data confirms the growing interest in natural antimicrobial drugs that are currently used in folk medicine or have the prospect of use in humane medicine in different countries of the world. Wide interest of the scientific community in the search for alternative antimicrobial agents, which would make it possible to overcome antibiotic resistance in the treatment of various types of diseases, has been revealed. Current scientific research has confirmed or disproved the effectiveness of only a thousandth part of all possible plants. Undoubtedly, the use of natural plant components will make it possible to make the treatment process cheaper and more effective, so this direction of research is currently very promising from all points of view.

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Section: Edible Plantssupporting

confidence: 78%

Antimicrobial activity of saponin-containing plants: review

Alina,

Kiełb Ewa,

František

2023

JDVAR

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“…On the other side zone of inhibition was calculated to determine the antibacterial activity of the different extracts. All the extracts showed antibacterial activity (Kalia et al 2020;Chan et al 2011;Pradhan and Dubey 2020). The maximum zone of inhibition was shown by T. arjuna against S. aureus (22 mm) and H. influenza (21 mm), followed by V. vinifera against S. pyogenes (20 mm), H. influenza (21 mm), and S. aureus (18 mm) and T. chebula against S. pyogenes (21 mm).…”

Section: Discussionmentioning

confidence: 99%

“…Simultaneously, a minimum inhibitory zone of T. chebula was observed against H. influenza (10 mm) and S. aureus (14 mm). The zone of inhibition result suggests that the extract contains bioactive compounds that will directly affect the S. pyogenes, H. influenza, and S. aureus destruction (Adeshina et al 2014;Bardia et al 2007;Kaushik 2019;Pradhan and Dubey 2020).…”

Section: Discussionmentioning

confidence: 99%

Herbal antibacterial remedy against upper respiratory infection causing bacteria and in vivo safety analysis

Singh

Agarwal

2021

Vegetos

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In the present study, the antibacterial activity and in vivo acute toxicity of five different extracts was analyzed. The Minimum Inhibitory Concentration and antibacterial activity of five different extracts, including Terminalia chebula, Camellia sinensis, Glycyrrhiza glabra, Vitis vinifera, and Terminalia arjuna, against three different bacterial species, namely, Streptococcus pyogenes, Haemophilus influenza, and Staphylococcus aureus was analyzed by broth dilution method and agar well diffusion method, respectively. The in vivo acute oral toxicity was analyzed by using Wistar rats. The antibacterial activity of different extracts was calculated by analyzing the zone of inhibition, and the maximum zone of 22 mm and minimum zone of 10 mm were observed against the different upper respiratory infections causing bacteria. The lowest MIC (0.8 mg/ml) found was of Camellia sinensis against the Streptococcus pyogenes and Staphylococcus aureus. No sign of toxicity and mortality was observed during the 14 days of study. The in vitro results of the tested extracts indicate that they possessed antibacterial activity and were found non-toxic. So, it can be used as an alternative for the treatment of upper respiratory infection-causing bacteria.

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“…Another investigation focused on the antimicrobial properties of methanol extract from tea ( Camellia sinensis ), revealing its inhibitory impact on various microorganisms, including E. coli, C. albicans, K. pneumoniae, S. aureus, S. typhi , and L. monocytogenes . Phytochemical analysis of the tea extract identified the presence of saponins (Pradhan & Dubey, 2020). The phytochemical screening of the aqueous extract from Kyllinga nemoralis revealed the existence of saponins.…”

Section: Saponins' Role In Anti‐inflammation Through Shaping the Gut ...mentioning

confidence: 99%

Critical review on anti‐inflammation effects of saponins and their molecular mechanisms

Wijesekara,

Luo,

2024

Phytotherapy Research

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This review highlights the increasing interest in one of the natural compounds called saponins, for their potential therapeutic applications in addressing inflammation which is a key factor in various chronic diseases. It delves into the molecular mechanisms responsible for the anti‐inflammatory effects of these amphiphilic compounds, prevalent in plant‐based foods and marine organisms. Their structures vary with soap‐like properties influencing historical uses in traditional medicine and sparking renewed scientific interest. Recent research focuses on their potential in chronic inflammatory diseases, unveiling molecular actions such as NF‐κB and MAPK pathway regulation and COX/LOX enzyme inhibition. Saponin‐containing sources like Panax ginseng and soybeans suggest novel anti‐inflammatory therapies. The review explores their emerging role in shaping the gut microbiome, influencing composition and activity, and contributing to anti‐inflammatory effects. Specific examples, such as Panax notoginseng and Gynostemma pentaphyllum, illustrate the intricate relationship between saponins, the gut microbiome, and their collective impact on immune regulation and metabolic health. Despite promising findings, the review emphasizes the need for further research to comprehend the mechanisms behind anti‐inflammatory effects and their interactions with the gut microbiome, underscoring the crucial role of a balanced gut microbiome for optimal health and positioning saponins as potential dietary interventions for managing chronic inflammatory conditions.

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Evaluation of phytochemical, antimicrobial and time-killing assay of Camellia species

Cited by 8 publications

References 26 publications

Antimicrobial activity of saponin-containing plants: review

Antimicrobial activity of saponin-containing plants: review

Herbal antibacterial remedy against upper respiratory infection causing bacteria and in vivo safety analysis

Critical review on anti‐inflammation effects of saponins and their molecular mechanisms

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