Evaluation of Potential Donors in Living Donor Liver Transplantation

Selection and outcome of the potential live liver donor

“…In a multi-center study, 60 % of the donors were rejected, and there was a wide variation in the donor rejection rates between the nine evaluating centers [5]. In a recent study [10], the donor acceptance rate was similar (32 %); however, inadequate FLR (43 %) and fatty liver (38.4 %) were the most common reasons for unsuitability of liver donation. In the present study, 23.5 % of donors did not proceed to donation because of reluctance after explaining the risks, and this was the most common donor-related reason for rejection.…”

Evaluation of donor workups and exclusions in a single‐center experience of living donor liver transplantation

“…The upper age limit for donation is usually between 55 and 65 years old . The major concern for donation from elderly people is age‐related morbidity and the quality of the donated organ .…”

“…A labor‐intensive LDLT program may also carry ethical controversies . Therefore, an adequate and thorough selection process is a major prerequisite for donor safety while at the same time providing a suitable graft to ensure a better recipient outcome …”

“…It should also reveal any conditions that predispose a healthy donor to any intraoperative or postoperative complications . The exclusion rate during an evaluation process has been reported to range from 60% to 86% . This differs according to the social setting, medical environment, and center policy.…”

“…(3)(4)(5) Therefore, an adequate and thorough selection process is a major prerequisite for donor safety while at the same time providing a suitable graft to ensure a better recipient outcome. (6)(7)(8)(9)(10) Donor evaluation allows the identification of factors associated with donor mortality and the development of strategies to mitigate the incidence. (11) It should also reveal any conditions that predispose a healthy donor to any intraoperative or postoperative complications.…”