Evaluation of sleep quality and restless legs syndrome in adult patients with sickle cell anemia

Erdem, Nazan Şimşek; Erdem, Ramazan; Oktay, Gönül; Kurtoğlu, Erdal

doi:10.1007/s11325-020-02185-z

Cited by 2 publications

(2 citation statements)

References 26 publications

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“…Finally, it was confirmed that the low hemoglobin level was an independent risk predictor, so it can be used as a significant biomarker of sleep disorders. Despite some studies have shown that sickle cell anemia is closely associated with restless withdrawal syndrome and obstructive sleep apnea in specific sleep disorders (Rosen et al, 2014;Erdem et al, 2020), the association between anemia and non-specific sleep disorders is poorly understood. Our research explored this issue and confirmed that anemia is potentially linked to nonspecific sleep disorders.…”

Section: Discussionmentioning

confidence: 99%

Development and Validation of a Clinical Prediction Model for Sleep Disorders in the ICU: A Retrospective Cohort Study

Zhao

Yang

et al. 2021

Front. Neurosci.

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BackgroundSleep disorders, the serious challenges faced by the intensive care unit (ICU) patients are important issues that need urgent attention. Despite some efforts to reduce sleep disorders with common risk-factor controlling, unidentified risk factors remain.ObjectivesThis study aimed to develop and validate a risk prediction model for sleep disorders in ICU adults.MethodsData were retrieved from the MIMIC-III database. Matching analysis was used to match the patients with and without sleep disorders. A nomogram was developed based on the logistic regression, which was used to identify risk factors for sleep disorders. The calibration and discrimination of the nomogram were evaluated with the 1000 bootstrap resampling and receiver operating characteristic curve (ROC). Besides, the decision curve analysis (DCA) was applied to evaluate the clinical utility of the prediction model.Results2,082 patients were included in the analysis, 80% of whom (n = 1,666) and the remaining 20% (n = 416) were divided into the training and validation sets. After the multivariate analysis, hemoglobin, diastolic blood pressure, respiratory rate, cardiovascular disease, and delirium were the independent risk predictors for sleep disorders. The nomogram showed high sensitivity and specificity of 75.6% and 72.9% in the ROC. The threshold probability of the net benefit was between 55% and 90% in the DCA.ConclusionThe model showed high performance in predicting sleep disorders in ICU adults, the good clinical utility of which may be a useful tool for providing clinical decision support to improve sleep quality in the ICU.

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Section: Discussionmentioning

confidence: 99%

Development and Validation of a Clinical Prediction Model for Sleep Disorders in the ICU: A Retrospective Cohort Study

Zhao

Yang

et al. 2021

Front. Neurosci.

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“…High quality, sufficient sleep contributes to overall health, 171 while insomnia and poor sleep contribute to hypertension, diabetes, obesity, depression, heart disease, strokes, infections and cancer. 171,172 In SCD, symptom burden, restless leg syndrome 173 and sleep apnoea have potential to cause uniquely high rates of insomnia. Moscou-Jackson 174,175 surveyed 263 Adult African-American patients with SCD and based on a 7-item self-report found a 41% rate of insomnia, and significant relationships between insomnia and self-reported life impact from pain and depression.…”

Section: Sl E Ep a N D Fatigu Ementioning

confidence: 99%

Psychiatric comorbidities in adults with sickle cell disease: A narrative review

Mishkin

Prince²,

Leimbach

et al. 2023

Br J Haematol

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SummaryAlthough descriptions of quality of life and patient reports of mood in sickle cell disease (SCD) have become more common in the literature, less is known about psychiatric illness prevalence, presentation, and treatment, particularly for adults. We provide a narrative review of what is known about common and debilitating psychiatric conditions such as depression, anxiety, and cognitive impairment, specifically for adults with SCD. We discuss the limitations of the current evidence, make provisional recommendations, and identify opportunities for research and improved care.

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Evaluation of sleep quality and restless legs syndrome in adult patients with sickle cell anemia

Cited by 2 publications

References 26 publications

Development and Validation of a Clinical Prediction Model for Sleep Disorders in the ICU: A Retrospective Cohort Study

Development and Validation of a Clinical Prediction Model for Sleep Disorders in the ICU: A Retrospective Cohort Study

Psychiatric comorbidities in adults with sickle cell disease: A narrative review

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