Evaluation of surrogate measures of pulmonary function derived from electrical impedance tomography data in children with cystic fibrosis

Muller, Peter A.; Mueller, Jennifer L.; Mellenthin, Michelle M.; Murthy, R.; Capps, Michael; Wagner, Brandie D.; Alsaker, Melody; Deterding, Robin R.; Sagel, Scott D.; Hoppe, Jordana E.

doi:10.1088/1361-6579/aab8c4

Cited by 30 publications

(30 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The regularization is accomplished via low-pass filtering in the scattering transform with a cutoff frequency dependent upon the noise level. The effect of domain-shape modeling and measurement errors on the 2-D D-bar method was analyzed in [107], and the method was used in the analysis of clinical data in [108,109].…”

Section: D-barmentioning

confidence: 99%

“…They compared these regions from two CF children to their chest CT and found that these regions were correlated to an air trapping area in CT images. The same group also used EIT to assess the response to intravenous antibiotic treatment for acute pulmonary exacerbations in CF [109]. Wettstein et al [175] investigated the effect of breathing aids in CF patients and suggested that EIT might be used to individualize respiratory physiotherapy.…”

Section: Applications In Patients With Obstructive Lung Diseasesmentioning

confidence: 99%

See 1 more Smart Citation

A review of electrical impedance tomography in lung applications: Theory and algorithms for absolute images

Martins

Sato

Moura

et al. 2019

Annual Reviews in Control

View full text Add to dashboard Cite

Electrical Impedance Tomography (EIT) is under fast development, the present paper is a review of some procedures that are contributing to improve spatial resolution and material properties accuracy, admitivitty or impeditivity accuracy. A review of EIT medical applications is presented and they were classified into three broad categories: ARDS patients, obstructive lung diseases and perioperative patients. The use of absolute EIT image may enable the assessment of absolute lung volume, which may significantly improve the clinical acceptance of EIT. The Control Theory, the State Observers more specifically, have a developed theory that can be used for the design and operation of EIT devices. Electrode placement, current injection strategy and electrode electric potential measurements strategy should maximize the number of observable and controllable directions of the state vector space. A non-linear stochastic state observer, the Unscented Kalman Filter, is used directly for the reconstruction of absolute EIT images. Historically, difference images were explored first since they are more stable in the presence of modelling errors. Absolute images require more detailed models of contact impedance, stray capacitance and properly refined finite element mesh where the electric potential gradient is high. Parallelization of the forward *

show abstract

Section: D-barmentioning

confidence: 99%

Section: Applications In Patients With Obstructive Lung Diseasesmentioning

confidence: 99%

A review of electrical impedance tomography in lung applications: Theory and algorithms for absolute images

Martins

Sato

Moura

et al. 2019

Annual Reviews in Control

View full text Add to dashboard Cite

show abstract

“…Reconstructions were computed using an iterative Gauss-Newton (GN) algorithm for the experimental tank data and by the D-bar method and Calderón's method for human subject data to demonstrate the suitability of the data for use with algorithms. We chose to use the D-bar and Calderón algorithms for reporting results on human subjects because of their ability to provide fast (real-time) reconstructions [46], [47] without the need for an accurate computation forward model (such as a finite-element method on a fine mesh) and because this combination of hardware and software has been used in our clinical studies in collaboration with CHCO [48] . It is not the purpose of this paper to compare the accuracy and performance of the reconstruction algorithms.…”

Section: Section IV Reconstructionsmentioning

confidence: 99%

The ACE1 Electrical Impedance Tomography System for Thoracic Imaging

Mellenthin

Mueller

Camargo

et al. 2019

IEEE Trans. Instrum. Meas.

Self Cite

View full text Add to dashboard Cite

The design and performance of the active complex electrode (ACE1) electrical impedance tomography system for single-ended phasic voltage measurements are presented. The design of the hardware and calibration procedures allows for reconstruction of conductivity and permittivity images. Phase measurement is achieved with the ACE1 active electrode circuit which measures the amplitude and phase of the voltage and the applied current at the location at which current is injected into the body. An evaluation of the system performance under typical operating conditions includes details of demodulation and calibration and an in-depth look at insightful metrics, such as signal-to-noise ratio variations during a single current pattern. Static and dynamic images of conductivity and permittivity are presented from ACE1 data collected on tank phantoms and human subjects to illustrate the system's utility.

show abstract

“…The most developed and widespread use of EIT is for pulmonary imaging, for which the literature is extensive, and we refer to the review articles [Frerichs 2017, Martins 2019, Nguyen 2012, Frerichs 2000] for more information. EIT is especially suitable for bedside pulmonary monitoring or for patients with chronic respiratory disease because it is noninvasive, non-ionizing, and an image can be produced in real time and obtained simultaneously with pulmonary function tests [Muller 2018].…”

Section: Introductionmentioning

confidence: 99%

A 3D Reconstruction Algorithm for Real-time Simultaneous Multi-Source EIT Imaging for Lung Function Monitoring

Kao¹,

Amm²,

Isaacson

et al. 2020

Preprint

View full text Add to dashboard Cite

Monitoring regional pulmonary ventilation and pulsatile perfusion changes in a 3D region of interest (ROI) of the lung is a promising application for electrical impedance tomography (EIT). This paper describes a 3D analytical reconstruction algorithm that was embedded in a prototype EIT system to enable a real-time image reconstruction at nearly 20 frames per second for monitoring impedance changes in the chest in real-time. The derivation and results of the 3D analytical forward solution and inverse solution and details of the real-time reconstruction algorithm are given. The algorithm and EIT system are validated with simulated data, in-vitro phantoms, and finally shown to be capable of imaging ventilation and pulsatile perfusion in human subjects. The human subject data was obtained using a high-precision, high-speed and simultaneous multiple current source (SMS-EIT) developed by GE Research. Data was collected using four rows of 8 electrodes for a healthy adult male subject and 2 rows of 16 electrodes for six healthy human female subjects, with one row placed above the breasts and a second row placed at the infra-mammary fold. Each of the female subjects performed a breathing maneuver with a volumetric incentive spirometer, and the volume of air inhaled was calculated from the EIT images. Pulsatile perfusion images were computed from this data, and regional lung filling was also analyzed.

show abstract

Evaluation of surrogate measures of pulmonary function derived from electrical impedance tomography data in children with cystic fibrosis

Cited by 30 publications

References 46 publications

A review of electrical impedance tomography in lung applications: Theory and algorithms for absolute images

A review of electrical impedance tomography in lung applications: Theory and algorithms for absolute images

The ACE1 Electrical Impedance Tomography System for Thoracic Imaging

A 3D Reconstruction Algorithm for Real-time Simultaneous Multi-Source EIT Imaging for Lung Function Monitoring

Contact Info

Product

Resources

About