Evaluation of the Effect of Phyto-Adaptogens on the Performance Capability of Outbred Female Mice

Abstract

The effect of Eleutherococcus senticosus, Rhaponticum carthamoides and Schisandra chinensis extracts in doses of 10, 25, 50 and 75 mg/kg were studied. The actoprotective activity the studied adaptogens was assessed on outbred female mice in a forced swim test with a load of 10% of the animal's body weight. Dry extracts of Eleutherococcus senticosus (50 mg/kg), Rhaponticum carthamoides (10 mg/kg) and Schisandra chinensis (25 mg/kg) were found to exhibit the most pronounced actoprotective activity.