Evaluation of the effectiveness of an intervention program on preventing childhood obesity in Denizli, Turkey

Sevinç, Özgür; Bozkurt, Ali İhsan; Gündoğdu, Mehmet; Aslan, Ümmühan Baş; Ağbuğa, Bülent; Aslan, Şehmus; Dikbaş, Emel; Gökçe, Zeliha

doi:10.3906/sag-1009-1179

Cited by 12 publications

(5 citation statements)

References 14 publications

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“… Cost: NR Sahota 2019 189 England Design: C-RCT (School) Setting: School Age group: 6-12 (year 2 intv = 6·2, control = 6·3; year 4 = 8·3; overall 7·2) Gender: mixed 358 311 Arms: 1 Target: DPA Theory: Behaviour Theory, BCW Duration: > 12 months Control: Usual practice BMI-z (> 12 months)† Adverse assessed: Yes Adverse effect: Body shape and dieting behavior (results suggest no negative impact) Cost: NR Sallis 1993 190 USA Design: C-RCT (School) Setting: School Age group: 6-12 (9·25) Gender: mixed 745 549 Arms: 2 Target: PA Theory: Behaviour Change and self-management Duration: > 12 months Control: Usual care PE BMI (> 12 months) Adverse: NR Cost: NR Salmon 2008 191 Australia Design: C-RCT (Classroom) Setting: School Age group: 6-12 (10·7) Gender: mixed 295 268 Arms: 3 Target: PA Theory: SCT and Behavioural Choice theory Duration: ≤ 12 months Control: Usual care curriculum BMI (≤ 12 months) Adverse assessed: Yes Adverse effect: Happiness with body weight and shape and eating to gain or lose weight (no effect). Cost: NR Santos 2014 192 Canada Design: C-RCT (School) Setting: School Age group: 6-12 (intv = 9·3, control = 8·8) Gender: mixed 687 647 Arms: 1 Target: DPA Theory: NR Duration: ≤ 12 months Control: Usual care regular curriculum BMI-z (≤ 12 months)† Adverse: NR Cost: NR Sekhavat 2014 193 Canada Design: RCT Setting: Health care service Age group: 6-12 years (8·9) Gender: mixed 168 106 Arms: 1 Target: DPA Theory: NR Duration: ≤ 12 months Control: Waitlist BMI-z (≤ 12 months) Adverse: NR Cost: NR Sevinc 2011 194 Turkey Design: C-RCT (group – 2 schools in each group schools) Sett...…”

Section: Resultsmentioning

confidence: 99%

Interventions to prevent obesity in school-aged children 6-18 years: An update of a Cochrane systematic review and meta-analysis including studies from 2015–2021

Hodder

O’Brien²,

Lorien³

et al. 2022

eClinicalMedicine

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Section: Resultsmentioning

confidence: 99%

Interventions to prevent obesity in school-aged children 6-18 years: An update of a Cochrane systematic review and meta-analysis including studies from 2015–2021

Hodder

O’Brien²,

Lorien³

et al. 2022

eClinicalMedicine

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“…The prevalence of obesity in Turkey has exceeded the critically high rate of 30%, and it is more prevalent in females. Studies in Eastern Turkey which covered our region have found similar prevalence of obesity and overweight rates (Sevinç, 2011;Yilmaz, 2019). Obesity has been found to be associated with an increased risk of premature death due to a significantly increased risk of developing diabetes, hypertension, coronary heart disease, stroke and several types of cancer (Yao, 2014).…”

Section: Introductionmentioning

confidence: 52%

Investigation of the Relationship between IL-6, IL-6R and CXCL5 Polymorphisms and Obesity in Denizli Province of Turkey

Arıkan¹,

Demirel²

2022

GenApp

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Obesity and its effects on increasing morbidity and mortality have reached the level of an epidemic with a high frequency in modern populations. IL-6 released from adipose tissue is known to trigger the chronic inflammation in obesity. CXCL5, which mediates the activation and migration of neutrophils, has been found at high levels in obese subjects. In our study, we aimed to investigate the possible effects of IL-6, IL-6R and CXCL5, polymorphisms and haplotypes on the development of obesity. We studied IL-6, rs2069827 (-1363, G/T), rs1800797 (-597, G/A), rs1800796 (-572, G/C) and rs1800795 (-174, G/C), IL-6R rs4845617 (-183, G/A), rs2228145 (+48892, A/C) and CXCL5 rs352046 (-156, G/C) polymorphic sites in 60 obesity patients and 59 healthy controls. For genotyping we used PCR-RFLP based approach. The IL-6 rs1800796, rs1800795 and IL-6R rs4845617 G allelles could be the possible genetic factors responsible for obesity. We found similar results in female obese group. The results indicated that there was no association between obesity and other SNPs (rs2069827, rs1800797, and rs1800795 and rs2228145) and CXCL5, rs352046. The results of IL-6 and IL-6R haplotype analysis by global differentiation test showed that haplotypes may have different distributions between obese and controls. Our results showed that polymorphisms and possible haplotypes in IL-6 and IL-6R genes, which have an important role in inflammation, may affect the development of obesity. This study points out the necessity of investigating the possible effects of gene polymorphisms of other cytokines and their receptors in the development of obesity in larger populations.

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“…The majority of included studies were cluster randomized ( N = 72/84) with the most common level of randomization being schools ( N = 56). Most studies ( n = 72) included only one intervention arm, though six 25,36,55,73,88,98 included two intervention arms, five included three intervention arms, 28,72,79,82,87 and one study included five intervention arms 94 …”

Section: Resultsmentioning

confidence: 99%

“…Most studies (n = 72) included only one intervention arm, though six 25,36,55,73,88,98 included two intervention arms, five included three intervention arms, 28,72,79,82,87 and one study included five intervention arms. 94 Half…”

Section: Study Characteristicsmentioning

confidence: 99%

Childhood obesity prevention trials: A systematic review and meta‐analysis on trial design and the impact of type 1 error

Padgett,

Stevens,

Summerbell

et al. 2024

Obesity Reviews

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SummaryEffect sizes from previously reported trials are often used to determine the meaningful change in weight in childhood obesity prevention interventions because information on clinically meaningful differences is lacking. Estimates from previous trials may be influenced by statistical significance; therefore, it is important that they have a low risk of type 1 error. A systematic review and meta‐analysis were conducted to report on the design of child obesity prevention randomized controlled trials and effectiveness according to risk of type 1 error. Eighty‐four randomized controlled trials were identified. A large range of assumptions were applied in the sample size calculations. The most common primary outcome was BMI, with detectable effect size differences used in sample size calculations ranging from 0.25 kg/m2 (followed up at 2 years) to 1.1 kg/m2 (at 9 months) and BMI z‐score ranging from 0.1 (at 4 years) to 0.67 (at 3 years). There was no consistent relationship between low risk of type 1 error and reports of higher or lower effectiveness. Further clarity of the size of a meaningful difference in weight in childhood obesity prevention trials is required to support evaluation design and decision‐making for intervention and policy. Type 1 error risk does not appear to impact effect sizes in a consistent direction.

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Evaluation of the effectiveness of an intervention program on preventing childhood obesity in Denizli, Turkey

Cited by 12 publications

References 14 publications

Interventions to prevent obesity in school-aged children 6-18 years: An update of a Cochrane systematic review and meta-analysis including studies from 2015–2021

Interventions to prevent obesity in school-aged children 6-18 years: An update of a Cochrane systematic review and meta-analysis including studies from 2015–2021

Investigation of the Relationship between IL-6, IL-6R and CXCL5 Polymorphisms and Obesity in Denizli Province of Turkey

Childhood obesity prevention trials: A systematic review and meta‐analysis on trial design and the impact of type 1 error

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