Evaluation of the efficacy of low-level light therapy using 1072 nm infrared light for the treatment of herpes simplex labialis

Dougal, Gordon; Lee, S. Y.

doi:10.1111/ced.12069

Cited by 26 publications

(30 citation statements)

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“…Transmission may occur via contact with an infected person. The virus remains in a latent state in neural tissues, and internal or external stimuli such as stress, immunosuppression, high fever, trauma, and ultraviolet light can trigger recurrences (2). …”

Section: Discussionmentioning

confidence: 99%

“…In addition, these agents should be administered several times on consecutive days that can have even sometimes interactions with other medications (2). …”

Section: Discussionmentioning

confidence: 99%

“…The pain often exists during the first two days (1). Internal or external stimuli such as stress, immunosuppression, high fever, trauma, and ultraviolet light can trigger recurrences (2). The lesions usually resolve within 7 to 10 days (3).…”

Section: Introductionmentioning

confidence: 99%

“…Dougal and Lee (2) assigned 87 patients with herpes labialis randomly in two groups. They used low level laser, 1072 nm, for the experimental group.…”

Section: Introductionmentioning

confidence: 99%

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Comparing the effect of diode laser against acyclovir cream for the treatment of herpes labialis

Honarmand¹,

Farhad-Mollashahi²,

Vosoughirahbar³

2017

J Clin Exp Dent

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BackgroundRecently alternative therapies such as the use of diode laser therapy have been introduced for recurrent herpes labial infection. The aim of this study was to evaluate the effectiveness of diode laser for treatment of recurrent herpes labialis.Material and MethodsThis was single-blind randomized clinical trial to evaluate the efficacy of diode laser for the treatment of recurrent herpes labial. In total, 60 patients whit recurrent herpes simplex labialis were selected and randomly divided in to three groups. 20 patients received treatment whit diode laser (at a wavelength of 870 nm, energy density 4.5 j/cm2), 20 patients were treated with acyclovir cream 5%, 20 patients received treatment with laser-off (placebo). The end point was lesions crusting. Data analyzed by Tukey HSD Test and One-way ANOVA (at a significance level of 0.05) in SPSS-20 software.ResultsThe mean length of recovery time (day) in the laser, off laser, and acyclovir groups was 2.20±0.41, 4.30±1.03, and 3.4±1.142, respectively. There is a significant difference between three groups in this regard (P<0.0001). The mean duration of pain (day) was 1.35±0.74, 2.65±1.27, and 2.30±0.92 for laser, off laser, and acyclovir groups, respectively (P<0.0001).ConclusionsTreatment with diode laser reduced the length of recovery time and pain severity faster than treatment with acyclovir cream. Key words:Recurrent herpes labial, Acyclovir, Low level laser therapy.

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Section: Discussionmentioning

confidence: 99%

“…In addition, these agents should be administered several times on consecutive days that can have even sometimes interactions with other medications (2). …”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Dougal and Lee (2) assigned 87 patients with herpes labialis randomly in two groups. They used low level laser, 1072 nm, for the experimental group.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Comparing the effect of diode laser against acyclovir cream for the treatment of herpes labialis

Honarmand¹,

Farhad-Mollashahi²,

Vosoughirahbar³

2017

J Clin Exp Dent

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“…(Carvalho et al, 2010;Bello-Silva et al, 2010;Eduardo et al, 2012;Muñoz-Sanchez et al, 2012;de Paula Eduardo et al, 2014;Dougal;Lee, 2013;Stona et al, 2014).…”

Section: Discussionunclassified

Detecção dos herpesvirus humanos na mucosa oral de pacientes irradiados para tratamento de carcinoma epidermoide em região de cabeça e pescoço

Palmieri¹

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Palmieri M. Detecção dos herpesvirus humanos na mucosa oral de pacientes irradiados para tratamento de carcinoma epidermoide em região de cabeça e pescoço. Dissertação apresentada à Faculdade de Odontologia da Universidade de São Paulo, para obter o título de Mestre, pelo Programa de Pós-Graduação em Ciências Odontológicas. A radioterapia para tratamento das neoplasias malignas em região de cabeça e pescoço é acompanhada de diversas complicações, decorrentes do comprometimento dos tecidos radiossensíveis localizados próximos ao tumor.Entre essas complicações a mucosite é a que merece maior destaque. A mucosite é uma reação tóxica inflamatória da mucosa oral causada pelo tratamento citorredutivo induzido pela radioterapia (RT) ou pela quimioterapia (QT). Ela manifesta-se com sinais de edema, eritema, úlcera e formação pseudomembrana, resultando em sintomas de ardência, que pode progredir para dor intensa e consequente prejuízo na alimentação e comunicação verbal.Infecções bacterianas, fúngicas ou virais podem acometer a mucosa bucal irradiada e exacerbar a manifestação da mucosite oral por meio da ativação de fatores de transcrição da resposta inflamatória. Existem poucos dados na literatura sobre a participação dos herpesvirus humanos na mucosite oral induzida pela radioterapia. A proposta desse trabalho foi avaliar a excreção oral dos herpesvirus humanos (HSV-1, HSV-2, EBV, CMV, VZV, HHV6, HHV7 e HHV8) e sua possível associação com o desenvolvimento e agravamento da mucosite oral, em pacientes diagnosticados com carcinoma epidermoide (CEC)de boca e orofaringe, submetidos à radioterapia associado à quimioterapia.Nesse estudo foram analisadas 158 amostras de lavado bucal, de 20 pacientes, submetidos à radioterapia para CEC em região de cabeça e pescoço, coletadas semanalmente, durante todo o tratamento. Foi realizada a extração do DNA dessas amostras e em seguida sua amplificação através da PCR utilizando dois conjuntos de primers: HSVP1/P2 para os subtipos HSV-1, HSV-2, EBV, CMV e HHV-8 e o VZVP1/P2 para os subtipos VZV, HHV-6 e HHV-7. As amostras positivas foram submetidas à digestão enzimática com enzimas de restrição BamHI e BstUI para determinação específica de cada um dos oito herpesvirus. Foi também avaliada clinicamente, a mucosite oral, em cada uma das coletas, seguindo os critérios da OMS e NCIC. As análises da amostra mostraram a excreção do EBV, HHV-6 e HHV-7, em todas as semanas de tratamento radioterápico, enquanto que a excreção do HSV1 não pode ser observada no momento da triagem. Considerando-se todos os períodos em conjunto (Triagem, semanas On our study, we analyzed 158 oral rinsing samples, collected weekly, from 20 patients during the whole radiotherapy treatment for squamous cell carcinoma in head and neck. From these samples, we extracted the DNA and afterwards we amplified them with PCR using two sets of primers:HSVP1/P2 for the subtypes HSV-1, HSV-2, EBV, CMV, and HHV-8 and VZVP1/P2 for the subtypes VZV, HHV 6, and HHV-7. The positive samples were subjected to enzymatic digestion with Ba...

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LED Photomodulation for Reversal of Photoaging and Reduction of Inflammation

Weiß¹,

Geronemus²,

Granger³

et al. 2015

Cosmetic Dermatology

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Evaluation of the efficacy of low-level light therapy using 1072 nm infrared light for the treatment of herpes simplex labialis

Abstract: Compared with placebo treatment, the treatment of HSL lesions with 1072 nm infrared light significantly reduced healing time.

Cited by 26 publications

References 30 publications

Comparing the effect of diode laser against acyclovir cream for the treatment of herpes labialis

Comparing the effect of diode laser against acyclovir cream for the treatment of herpes labialis

Detecção dos herpesvirus humanos na mucosa oral de pacientes irradiados para tratamento de carcinoma epidermoide em região de cabeça e pescoço

LED Photomodulation for Reversal of Photoaging and Reduction of Inflammation

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