Evaluation of the Efficacy of Ablative vs. Fractional Er:YAG Laser Modes as a Treatment of Post-Burn Scars

Asfour, Abdel Rahman; Shokeir, Hisham; Elwakil, Tarek F.; Ghareeb, Fouad Mohammed; Elbasiouny, Mahmoud S.

doi:10.4172/0974-8369.1000415

Cited by 3 publications

(2 citation statements)

References 22 publications

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“…Asfour et al (2017) revealed statistically significant variations in vascularity, flexibility, height and pigmentation after treatment of 50 patients with post-burn scars with fractional ablative Er:YAG. These results go with our results except for pigmentation which showed no significant improvement either by VSS or POSAS [18].…”

Section: Discussionsupporting

confidence: 92%

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Comparison Between Er: Yag and Co2 Ablative Fractional Lasers in The Treatment of Keloid and Hypertrophic Scars: Histopathological, Immuno-Histochemical and Ultrastructural Study

Elsaid

Al-Tawel²,

Sabry³

et al. 2023

Benha Journal of Applied Sciences

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Background: Scarring is a frequent occurrence, since it results from skin damage in individuals of all ages. This work aimed compare clinical results and effect on histopathological architecture and expression of CTGF of the ablative fractional 10,600-nm CO 2 and 2,940 nm Er:YAG lasers in keloid and hypertrophic scars treatment. Methods: that randomized, prospective, double-blinded comparative study included 60 individuals (Fitzpatrick skin type II to V), that are diagnosed clinically and histopathologically with hypertrophic scars. Those were split into 2 groups; 30 patients in group I (Fractional Er:YAG laser), and 30 patients in group II (fractional CO 2 laser). Results: A substantial decrease in post treatment VSS with fractional ablative Er:YAG and Co2 lasers mostly as a result of improved vascularity, pliability and to a lesser extent in height with Er:YAG ,while after CO 2 improvement was significant in height and pliability only. Histopathological examination of skin biopsies in current study, showed that there were increased thickness of epidermis and irregular collagen bands replacement with parallel new collagen fibril organisation after fractional ablative Er:Yag. Immunohistochemical staining of CTGF showed significant reduction 6 months follwoing fractional Erbium YAG and CO2 laser treatment with prominent decrease after Fr Er: YAG. Conclusions: Fractional ablative lasers including both CO2 and Er:YAG have combined impressive ablative laser results with greater protection profile of nonablative lasers. Fractional ablative Er:YAG laser mainly improve vascularity and pliability of hypertrophic scars while Co2 improvement was significant in height and pliability.

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Section: Discussionsupporting

confidence: 92%

“…This is an indistinguishable result from those reported by Asfour et al (2017) who confirmed epidermal hyperplasia; hyperkeratosis, flat ridges and papilomatosis. Asfour et al (2017) also reported that Masson Trichrome stain showed compact, wellorganized collagen bundles in the papillary dermis parallel to the epidermis [18].…”

Section: Discussionmentioning

confidence: 93%

Comparison Between Er: Yag and Co2 Ablative Fractional Lasers in The Treatment of Keloid and Hypertrophic Scars: Histopathological, Immuno-Histochemical and Ultrastructural Study

Elsaid

Al-Tawel²,

Sabry³

et al. 2023

Benha Journal of Applied Sciences

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Lasers for the prevention and treatment of hypertrophic scars: a review of the literature

Rosenthal

Kolli

Israilevich

et al. 2020

Journal of Cosmetic and Laser Therapy

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Fractionally Ablative Er:YAG Laser Resurfacing for Thermal Burn Scars: a Split-Scar, Controlled, Prospective Cohort Study

Sipprell

Bell

Ibrahim

2020

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BACKGROUND Thermal burn scars can have catastrophic impact on the quality of life and personal image, and over time can lead to profound physical and psychological debilitation. There are no established treatments to significantly improve burn scars. OBJECTIVE To demonstrate the safety, efficacy, and tolerability of fractionally ablative Er:YAG resurfacing of mature burn scars. METHODS Sixteen subjects were enrolled and received 3 treatments of fractionally ablative Er:YAG resurfacing at monthly intervals. Twelve completed the study. Scars were scored with the Vancouver Scar Scale (VSS) by the patient and physician before and after treatment. Blinded photographic analysis (Visual Analog Scale [VAS]) and blinded histologic analysis of tissue before and after treatment was also performed. RESULTS Significant Improvement in VSS scores were seen in all 12 patients, reported by patients and the evaluating physician alike. Photographic analysis demonstrated subjective improvement in all 12 patients. Histologically, there was significant improvement in collagen architecture and the number of vessels per high-power field. The treatments were tolerated well by patients, and 1 superficial skin infection occurred. CONCLUSION Fractionally ablative Er:YAG laser resurfacing is a safe and effective modality in the treatment of thermal burn scars with subjective and objective improvement as seen from the patient and physician.

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Evaluation of the Efficacy of Ablative vs. Fractional Er:YAG Laser Modes as a Treatment of Post-Burn Scars

Cited by 3 publications

References 22 publications

Comparison Between Er: Yag and Co2 Ablative Fractional Lasers in The Treatment of Keloid and Hypertrophic Scars: Histopathological, Immuno-Histochemical and Ultrastructural Study

Comparison Between Er: Yag and Co2 Ablative Fractional Lasers in The Treatment of Keloid and Hypertrophic Scars: Histopathological, Immuno-Histochemical and Ultrastructural Study

Lasers for the prevention and treatment of hypertrophic scars: a review of the literature

Fractionally Ablative Er:YAG Laser Resurfacing for Thermal Burn Scars: a Split-Scar, Controlled, Prospective Cohort Study

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