“…Changes in hematopoiesis and hematotoxic effects, including altered blood cell counts and lymphocyte counts and immunotoxicity, are consistent indicators of benzene exposure (IRIS, 2002; McHale et al, 2012; OEHHA, 2014) and can be measured even after brief exposure periods (Kirkeleit et al, 2006). Of additional concern is that hematotoxicity from short‐term benzene exposure is associated with future risk of hematological cancers (IARC, 2018; McHale et al, 2012), indicating that there is likely no safe level of benzene exposure (Bae et al, 2018; Smith, 2010). Although the exact form of the exposure–response curve for benzene has been debated (Kim, Vermeulen, Waidyanatha, Johnson, Lan, Rothman, et al, 2006; Kim, Vermeulen, Waidyanatha, Johnson, Lan, Smith, et al, 2006; OEHHA, 2014; Rappaport et al, 2009; Smith, 2010), the USEPA cited studies indicating supralinear exposure‐response benzene at concentrations less than 1 ppm and used these data as primary evidence to lower benzene concentrations in gasoline formulations (Smith, 2010).…”