Evaluation of the fetal palate at 11 to 13 (+6) weeks of gestation based on an analysis of static ultrasound images using modern IT techniques

Abstract

The application of pattern analysis to a 2D frozen image is a new approach for prenatal diagnostics. This technique may be a helpful tool for physicians and could assist in the diagnosis of cleft palate.

Absent ‘superimposed‐line’ sign: novel marker in early diagnosis of cleft of fetal secondary palate

“…With the advent of 3D ultrasound imaging [20][21][22][23] , a variety of views of the fetal palate have been described, including the 'reverse-face' view 24 , the 'flipped-face' view 15 , 'angled insonation' 4 , the 'oblique-face' view 5 and, recently, the 'surface-rendered oropalatal (SROP)' view 25 . Recent techniques, such as the application of the volume nuchal translucency algorithm to assess the palate and the option of fetal magnetic resonance imaging in detecting isolated cleft palate, will be explored in future [26][27][28][29] . What we need for now, however, is a simple, but effective, 2D ultrasound marker that can serve as a robust screening tool for clefts of the secondary palate.…”

Understanding the distinction between cleft lip and cleft palate: a critical step for successful prenatal detection

“…Orofacial clefts (OCs), comprised of cleft lip with or without cleft palate (CL+/−P) and cleft palate without cleft lip (CP), are among the most common congenital anomalies [1,2,3 ▪▪ ,4]. While there is geographic, ethnic and sex variation [5–7], the most recent European prevalence data from registries between 2013 to 2019 indicates OCs occur in 12.86/10,000 live births. Specifically, CL+/−P and CP occur in 7.46 and 5.40 per 10,000 live births, respectively [8 ▪ ].…”