ObjectiveTo evaluate the effectiveness of rapid response teams using early
identification of clinical deterioration in reducing the occurrence of
in-hospital mortality and cardiorespiratory arrest.Data sourcesThe MEDLINE, LILACS, Cochrane Library, Center for Reviews and Dissemination
databases were searched.Study selectionWe included studies that evaluated the effectiveness of rapid response teams
in adult hospital units, published in English, Portuguese, or Spanish, from
2000 to 2016; systematic reviews, clinical trials, cohort studies, and
prepost ecological studies were eligible for inclusion. The quality of
studies was independently assessed by two researchers using the
Newcastle-Ottawa, modified Jadad, and Assessment of Multiple Systematic
Reviews scales.Data extractionsThe results were synthesized and tabulated. When risk measures were reported
by the authors of the included studies, we estimated effectiveness as 1-RR
or 1-OR. In pre-post studies, we estimated effectiveness as the percent
decrease in rates following the intervention.ResultsOverall, 278 studies were identified, 256 of which were excluded after
abstract evaluation, and two of which were excluded after full text
evaluation. In the meta-analysis of the studies reporting mortality data, we
calculated a risk ratio of 0.85 (95%CI 0.76 - 0.94); and for studies
reporting cardiac arrest data the estimated risk ratio was 0.65 (95%CI 0.49
- 0.87). Evidence was assessed as low quality due to the high heterogeneity
and risk of bias in primary studies.ConclusionWe conclude that rapid response teams may reduce in-hospital mortality and
cardiac arrests, although the quality of evidence for both outcomes is
low.