3-hydroxy-2-methyl-4-pyrone) is widely used as a flavour enhancer in foodstuffs and cosmetics. It particularly enhances soft-fruit flavours, pineapple and some chocolate flavours. It is also used in the manufacture of aromatic candles and in some pipe and cigarette tobacco. It showed no sensitization in 25 volunteers in a closed patch test with 10% pet. Neat maltol applied to a rabbit shows a slight irritant response. Our patient (case no. 1) therefore demonstrates a rare reaction.We have found no reports of strawberry flavouring sensitivity in the last 30 years, though strawberries themselves are well-recognized as a cause of contact and generalized urticaria. Our patients had no problems on contact with or on ingesting natural strawberries. No reaction has been noted with flavoured sweets, or with aromatic candles, and neither patient smoked.
Case Report
Lucker G P H, Hulsmans R-F H J, Van der Kley A M J,Van de Staak W B M. Evaluation of the frequency of contact allergy reactions to Kathon CG in the Maastricht area 1987 -1990 3. Frosch P J, Lahti A, Hannuksela M, Andersen K E, Wilkinson J D, Shaw·s, Lachapelle J M. Chloromethylisothiazolone/methylisothiazolone (CMIIMI) use test with a shampoo on patch test positive subjects. Contact Dermatitis