Evaluation of the healing effect of honey and colostrum in treatment of cutaneous wound in rat

Tanideh, Nader; Abdordideh, Ehsan; Yousefabad, Seyedeh Leili Asadi; Daneshi, Sajad; Hosseinabadi, Omid Koohi; Samani, Siamak; far, Amin Derakhshan

doi:10.1007/s00580-016-2347-5

Cited by 8 publications

(13 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It has a variety of clinical applications, including the treatment of bacterial and viral diarrhea, joint inflammation, sinusitis, pulmonary inflammation, and allergies. It has a range of antibacterial, antiviral, and anti‐inflammatory factors suitable for tissue repair and growth 197 . Among the growth factors presented in the colostrum, TGF‐β, PDGF, FGF, TGF‐α, and EGF, are effective in the process of wound healing and angiogenesis.…”

Section: Treatment Of Chronic Wounds Using Angiogenic Approachesmentioning

confidence: 99%

“…Research has shown that colostrum, in addition to accelerating wound healing, can contribute to wound closure via promoting granulating tissue formation, angiogenesis, increasing collagen synthesis, and proliferation of fibroblasts. Studies on the effect of local administration of colostrum ointment on the ulcers proved that it can accelerate the wound repair and wound closure, increase collagen synthesis, and vascularization 197,198 …”

Section: Treatment Of Chronic Wounds Using Angiogenic Approachesmentioning

confidence: 99%

“…Honey is found to prevent infection and inflammation and can lead to anti‐oxidant effects. Moreover, it protects the wounds against gram‐positive and gram‐negative bacteria and is also resistant to fungi 197,199 . Honey contains active biological agents, such as melitin, apamin, and adolapin, which could increase membrane permeability and affect the production of growth factors such as VEGF, TGF‐β1, and collagen synthesis 199‐201 …”

Section: Treatment Of Chronic Wounds Using Angiogenic Approachesmentioning

confidence: 99%

“…Animal studies have documented that owing to enhanced cell proliferation, angiogenesis, and collagen synthesis, honey decreases the formation of scar and improves the healing response 45,197 . Honey‐incorporated dressings, in comparison with colostrum, results in better healing, faster hemostasis, angiogenesis, less inflammation, more anti‐bacterial and anti‐oxidant activity, collagen production, proliferation of fibroblasts, epithelialization, and contraction of the ulcer 197,200,201 .…”

Section: Treatment Of Chronic Wounds Using Angiogenic Approachesmentioning

confidence: 99%

See 3 more Smart Citations

Skin wound healing assisted by angiogenic targeted tissue engineering: A comprehensive review of bioengineered approaches

Nour

Imani

Chaudhry

et al. 2020

J Biomedical Materials Res

View full text Add to dashboard Cite

Skin injuries and in particular, chronic wounds, are one of the major prevalent medical problems, worldwide. Due to the pivotal role of angiogenesis in tissue regeneration, impaired angiogenesis can cause several complications during the wound healing process and skin regeneration. Therefore, induction or promotion of angiogenesis can be considered as a promising approach to accelerate wound healing. This article presents a comprehensive overview of current and emerging angiogenesis induction methods applied in several studies for skin regeneration, which are classified into the cell, growth factor, scaffold, and biological/chemical compound‐based strategies. In addition, the advantages and disadvantages of these angiogenic strategies along with related research examples are discussed in order to demonstrate their potential in the treatment of wounds.

show abstract

Section: Treatment Of Chronic Wounds Using Angiogenic Approachesmentioning

confidence: 99%

Section: Treatment Of Chronic Wounds Using Angiogenic Approachesmentioning

confidence: 99%

Section: Treatment Of Chronic Wounds Using Angiogenic Approachesmentioning

confidence: 99%

Section: Treatment Of Chronic Wounds Using Angiogenic Approachesmentioning

confidence: 99%

See 2 more Smart Citations

Skin wound healing assisted by angiogenic targeted tissue engineering: A comprehensive review of bioengineered approaches

Nour

Imani

Chaudhry

et al. 2020

J Biomedical Materials Res

View full text Add to dashboard Cite

show abstract

“…GMJ.2020;9:e1759 www.gmj.ir Similar physiology and tissue organization in humans and rats make it possible that rat can be applied as a burn model to reveal human tissues' reactions under specific conditions [4]. Wound coverage using artificial, biological, and the mixed coating is very important [5]. Without it, an increase in the number of deaths, bacterial growth, and other complications will be observed [6].…”

Section: Introductionmentioning

confidence: 99%

Healing Effects of Human Amniotic Membrane and Burned Wool on the Second-degree Burn in Rats

Tanideh

Keshavarzi

Zadeh

et al. 2020

GMJ

Self Cite

View full text Add to dashboard Cite

ackground: This study aimed to compare sheep burnt wool and human amniotic membrane (AM) on second-degree burn wound healing in rats. Materials and Methods: Seventy-two adult male rats of Sprague Dawley underwent general anesthesia, and a deep second-degree burn was created on their skin by a hot iron plate. Afterward, human AM, silver sulfadiazine ointment (SSD), and sheep burned wool were used on wound area for burn treatment. On days 7, 14, and 21 of the experiment, the rats were sacrificed, and histopathological assessments were done. Results: Human AM, in comparison with other groups, significantly (P<0.05) showed better improvement in all pathologic variables. Burned wool showed significant improvement compared to the control group on day 7 in the angiogenesis, on day 14 in granulation tissue formation and epithelial formation, and on day 21 in new epithelial formation (P<0.05). Burned wool compared with SSD ointment in granulation tissue formation improved significantly (P<0.05) on days 7 and 14. Also, SSD ointment in comparison with the control group significantly improved (P<0.05) granulation tissue formation and macrophage on day 7. Conclusion: Human AM has a significant effect on the treatment of second-degree burn. Burned wool has a better effect on wound healing than SSD ointment and negative control group without treatment in terms of granulation tissue and epithelium formation. [GMJ.2020;9:e1759]

show abstract

Bovine Colostrum for Veterinary and Human Health Applications: A Critical Review

Ross

Stanton

2023

Annu. Rev. Food Sci. Technol.

View full text Add to dashboard Cite

Bovine colostrum harbors a diverse array of bioactive components suitable for the development of functional foods, nutraceuticals, and pharmaceuticals with veterinary and human health applications. Bovine colostrum has a strong safety profile with applications across all age groups for health promotion and the amelioration of a variety of disease states. Increased worldwide milk production and novel processing technologies have resulted in substantial growth of the market for colostrum-based products. This review provides a synopsis of the bioactive components in bovine colostrum, the processing techniques used to produce high-value colostrum-based products, and recent studies utilizing bovine colostrum for veterinary and human health.

show abstract

Evaluation of the healing effect of honey and colostrum in treatment of cutaneous wound in rat

Cited by 8 publications

References 21 publications

Skin wound healing assisted by angiogenic targeted tissue engineering: A comprehensive review of bioengineered approaches

Skin wound healing assisted by angiogenic targeted tissue engineering: A comprehensive review of bioengineered approaches

Healing Effects of Human Amniotic Membrane and Burned Wool on the Second-degree Burn in Rats

Bovine Colostrum for Veterinary and Human Health Applications: A Critical Review

Contact Info

Product

Resources

About