Evaluation of the in vitro α‐glucosidase inhibitory activity of green tea polyphenols and different tea types

Abstract

Green TPs, green tea, black tea and oolong tea are excellent α-glucosidase inhibitors and their inhibitory potency is mainly attributed to TPs. These findings suggest that green tea, black tea and oolong tea can potentially be used to control postprandial hyperglycemia.

Digestive enzyme inhibition activity of the phenolic substances in selected fruits, vegetables and tea as compared to black legumes

“…IC 50 values of green tea and black tea against a-glucosidase were reported as 2.82 and 2.25 lg/mL (Yang & Kong, 2016), which were much lower than the values determined in this study. Phenolic extractions from thirty-three cultivars of blueberry showed a-glucosidase inhibition but with no IC 50 values provided (Wang, Camp, & Ehlenfeldt, 2012).…”

High‐theabrownins instant dark tea product by Aspergillus niger via submerged fermentation: α‐glucosidase and pancreatic lipase inhibition and antioxidant activity

“…He et al reported that different molecular levels of TB (≤3.5, 3.5–25, 25–50, 50–100 and ≥ 100 kDa) had an effect on hypoglycemia, particularly 25–50 kDa TB, which was 1.9 times as active as acarbose. In addition, tea polysaccharides, tea polyphenols and theaflavins had an inhibitory effect on α ‐glucosidase activity.…”

Inhibitory Effects of Various Ratios of Polysaccharides/Alkaloids from Rhizome of <i>Coptis chinensis</i> Franch on α-Glucosidase

“…Thus, we selected acarbose as a positive reference drug in this study. The α-glucosidase inhibitory activity assay is commonly used for rapid in vitro screening of potential antidiabetes drugs [19,20,23].…”