2022
DOI: 10.1088/1361-6560/ac4fa4
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Evaluation of the impact of a scanner prototype on proton CT and helium CT image quality and dose efficiency with Monte Carlo simulation

Abstract: Objective: The use of ion computed tomography (CT) promises to yield improved relative stopping power (RSP) estimation as input to particle therapy treatment planning. Recently, proton CT (pCT) has been shown to yield RSP accuracy on par with state-of-the-art x-ray dual energy CT. There are however concerns that thelower spatial resolution of pCT compared to x-ray CT may limit its potential, which has spurred interest in the use of helium ion CT (HeCT). The goal of this study was to investigate image quality o… Show more

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Cited by 4 publications
(5 citation statements)
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“…This is a finer check of the calibration procedure than the one described in Scaringella et al (2023). In addition, the MAPE values, although achieved with a small number of materials, are lower than the one reported in Dedes et al (2022) and Götz et al (2022) with the same reconstruction algorithm, demonstrating a praiseworthy response of our detectors and calibration procedure.…”
Section: Discussionmentioning
confidence: 59%
See 1 more Smart Citation
“…This is a finer check of the calibration procedure than the one described in Scaringella et al (2023). In addition, the MAPE values, although achieved with a small number of materials, are lower than the one reported in Dedes et al (2022) and Götz et al (2022) with the same reconstruction algorithm, demonstrating a praiseworthy response of our detectors and calibration procedure.…”
Section: Discussionmentioning
confidence: 59%
“…Therefore, in this study the imaging performance of the INFN pCT was investigated in terms of spatial resolution, NPS and RSP accuracy, through a custom-built, synthetic phantom. The phantom design is similar to the one already used in performance analysis of other particle CT systems (Johnson et al 2016, Volz et al 2021, Götz et al 2022. However, the possibility to fill the phantom with liquid water is a novelty, as a step toward more realistic clinical conditions and similarities to biological phantoms that will be used to further work on the cross-calibration curve.…”
Section: Discussionmentioning
confidence: 99%
“…The MAPEs of the RSP inserts of the sensitometry module were found to be between 0.14% and 0.46% which is slightly below the value found in Dedes et al [30] (0.55% for measurement data and 0.69% for a corresponding Monte Carlo simulation), where distance-driven binning [4] was used for the reconstruction. In Götz et al [31] , a MAPE of 0.19% was reported for a reconstruction (using again distance-driven binning) of an ideal data set of the sensitometry module and 0.59% for a realistic data set (using a particle fluence of 104 protons per mm 2 per projection and a total of 360 projections).…”
Section: Discussionmentioning
confidence: 99%
“…To quantify the spatial resolution in the axial plane with and without IR tracking, we scanned a cylinder phantom along the SI direction and calculated the modulation transfer function (MTF) from the radial edge-spread function (ESF) for each slice in the SI direction. 33 The cylinder phantom was 152 mm in diameter and was scanned with a detector pixel size of 0.3 mm. For comparison, we also used a previous scan of a cylinder phantom with 140 mm diameter using Elekta's XVI CBCT system with a detector pixel size of 0.8 mm.…”
Section: Modulation Transfer Functionmentioning
confidence: 99%