Evaluation of the relationship of hemogram parameters with prognosis in older adults with acute abdominal pathologies

Abstract

Aim:We aimed to investigate the effects of hemogram parameters on the short-term mortality of older adults with acute abdominal pathologies. Secondly, it was aimed to investigate the effect of hemogram parameters on mortality in operated and non-operated patients. Material and Method: This retrospective observational study was conducted in an emergency medicine clinic between June 1, 2019, and June 1, 2020. Data on patients over 65 years of age who presented to the emergency department with acute abdominal pathologies were analyzed. Hemogram parameters, as in our patient group over 65 years old, who presented with all acute abdomen pathologies; It was examined in terms of its relationship with prognosis in our operated and non-operated patient group. Statistical analysis was performed using SPSS v. 26.0. Results:The study included a total of 744 patients, of whom 391(52.6%) were women. Mortality was seen in 114(15.32%) patients, and 83(11.2%) patients underwent surgery. AUC and cut off values are for leukocytes count 0.590 and 10.83 for neutrophils count 0.596 and 9.64 for neutrophil-lymphocyte ratio 0.606 and 8.24 to predict mortality (p=0.002, p=0.001, and p>0.001, respectively Conclusion: In this study, among the hemogram parameters; leukocytes, neutrophils and neutrophil-lymphocyte ratio were determined to have a statistically significant ability to predict mortality in older adults both operaple and non operabl groups groups presenting with acute abdominal pathologies, but their accuracy rates were low.

Sistemik immün inflamasyon indeksi, akut apandisitli hastalarında komlikasyonun doğru erken tahmini için yeni ve güçlü bir belirteç olabilir

“…Despite the discrepancies concerning the cut-off values, we believe that NLR is an important parameter in the diagnosis of AA and in differentiating between complicated and uncomplicated cases. SII, a new-generation comprehensive systemic inflammatory index, has been reported to be a prognostic marker in some malignant diseases, autoimmune diseases, such as Behçet's disease and ankylosing spondylitis, abdominal infections, and many other diseases and conditions, from low-level infection to sepsis 19,20,[26][27][28][29] . It has been suggested that SII is a more successful marker than PLR and NLR in showing inflammation and immune response [20][21][22][23][24][25][26][27] .…”