Evaluation of the safety of ivermectin-praziquantel administered orally to pregnant mares

Mercier, P.; Alves-Branco, Francisco; Sapper, Maria de Fatima; White, C. J.

doi:10.2460/ajvr.2003.64.1221

Cited by 3 publications

(1 citation statement)

References 12 publications

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“…0 mg/kg. Drug combinations, such as pyrantel pamoate/trichlorfon and praziquantel/moxidectin (Grubbs et al 2003) or praziquantel/ivermectin (Coles et al 2003 ;Rehbein et al 2003 ;Mercier et al 2003), can also be used for (endo/ectocidal) treatment against a broader spectrum of parasites. In addition to treatment strategies, control of A. perfoliata may also be complemented with pasture management.…”

Section: S E R O L O G I C a L D I A G N O S I Smentioning

confidence: 99%

Anoplocephala perfoliataof horses – significant scope for further research, improved diagnosis and control

2005

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Anoplocephala perfoliata is the commonest tapeworm parasite of horses and is incriminated as a significant cause of clinical disease (e.g., ileocaecal intussusception, caeco-caecal intussusception and/or caecal perforation), particularly in horses chronically infected with large numbers of worms. The high prevalence (approximately 20-80%) of the parasite in some countries suggests an increased risk of clinical cases. In spite of research, there is still a paucity of information regarding the pathogenesis of the disease, the epidemiology of the parasite in different geographical regions and there are significant limitations with the diagnosis of infection. The present article provides an account of the biology, epidemiology and pathogenic effects of A. perfoliata, the diagnosis of infection and treatment. It highlights some gaps in knowledge of the parasite and the disease it causes, and suggests opportunities for future research and prospects for improved diagnosis, prevention and control.

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Section: S E R O L O G I C a L D I A G N O S I Smentioning

confidence: 99%

Anoplocephala perfoliataof horses – significant scope for further research, improved diagnosis and control

2005

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Efficacy and safety of oral praziquantel against Dicrocoelium dendriticum in llamas

Dadak¹,

Wieser²,

Joachim³

et al. 2013

Veterinary Parasitology

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Praziquantel for the treatment of schistosomiasis mansoni during pregnancy

Adam¹,

Elwasila²,

Homeida

2005

Annals of Tropical Medicine & Parasitology

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In a prospective study carried out in New Halfa Teaching Hospital, in eastern Sudan, between June 2001 and April 2003, 25 pregnant Sudanese women with schistosomiasis mansoni were each treated with a single oral dose of praziquantel (PZQ), at 40 mg/kg. The drug was given to six (24%), 12 (48%) and seven (28%) of the women during the first, second and third trimesters of their pregnancies, respectively. The patients were followed-up until delivery and their babies were followed-up until they were 1 year old. Although one patient, who received PZQ after 10 weeks of gestation, aborted (3 weeks post-treatment), this frequency of abortion is similar to that seen in the local community. None of the treated women died, and there were no stillbirths or congenital abnormalities in the newborn babies. Although this is a small trial, it appears that PZQ is a safe drug to use against schistosomiasis mansoni, even during the first trimester of pregnancy.

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Evaluation of the safety of ivermectin-praziquantel administered orally to pregnant mares

Abstract: Administration of the ivermectin-praziquantel paste appears to be safe in pregnant mares and their foals.

Cited by 3 publications

References 12 publications

Anoplocephala perfoliataof horses – significant scope for further research, improved diagnosis and control

Anoplocephala perfoliataof horses – significant scope for further research, improved diagnosis and control

Efficacy and safety of oral praziquantel against Dicrocoelium dendriticum in llamas

Praziquantel for the treatment of schistosomiasis mansoni during pregnancy

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