Evaluation of third-trimester neutrophil-lymphocyte and platelet-lymphocyte ratios and their correlation with birth weight

Objectives: The present study attempted to evaluate the relationship between fetal growth restriction (FGR) and the platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) in singleton term pregnancy. Methods: We carried out this prospective, case-control study at a Training and Research Hospital in Türkiye between May 2021 and January 2023. We utilized ultrasonography to assess singleton pregnancy with FGR between 37-40 weeks of gestation and considered the patients’ last menstrual periods (LMD). Results: We recruited 250 pregnant women in the study and divided them into the FGR (n = 125) and healthy control (n = 125) groups. Our findings revealed no significant difference between the groups by age, body mass index (BMI), stillbirth history, abortion, tobacco use, and regular pregnancy monitoring (p > 0.05). Fetal birth weights and hospitalization in the neonatal intensive care unit (NICU) were also similar between the groups. Yet, 1- and 5-minute APGAR scores were significantly lower in the FGR group than in the control group. In addition, compared to the healthy subjects, the FGR group had significantly increased white blood cell, lymphocyte, neutrophil, platelet counts and NLR and PLR values, but mean platelet volume (MPV) remained similar. Conclusions: In a nutshell, our findings suggested that two noteworthy inflammatory markers, NLR and PLR, are likely to elevate in the presence of FGR.

show abstract

“…! inflammatory response was found to be related to low birth weight in the ongoing process [15][16][17][18][19][20][21][22][23][24][25][26][27].…”

Section: Discussionmentioning

confidence: 98%

Evaluation of umbilical cord blood hematological parameters in pregnant women with fetal growth restriction

DEMİR

ÇAM

et al. 2023

The European Research Journal

View full text Add to dashboard Cite

show abstract

Evaluation of third-trimester neutrophil-lymphocyte and platelet-lymphocyte ratios and their correlation with birth weight

Abstract: of Medicine (Decision number: 09.2021.99). All procedures in this study involving human participants were performed in accordance with the 1964 Helsinki Declaration and its later amendments.

Cited by 1 publication

References 25 publications

Evaluation of umbilical cord blood hematological parameters in pregnant women with fetal growth restriction

Evaluation of umbilical cord blood hematological parameters in pregnant women with fetal growth restriction

Contact Info

Product

Resources

About