Evaluation of tumor marker cancer antigen 72-4 (CA 72-4) in the monitoring of metastatic or recurrent tumors of the gastrointestinal tract, lung, breast, and ovaries.

Mariampillai, Anusiyanthan Isaac; Cruz, Josephine Pineda Dela; Suh, Jason; Sivapiragasam, Abirami; Nevins, Kyle; Hindenburg, Alexander

doi:10.1200/jco.2017.35.4_suppl.263

Cited by 8 publications

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“…But it elevates after metastatic and recurrent ovarian tumor. 10 Another interesting case was followed in another centre for obesity and excessive weight gain in a 16-year-old girl. Since the patient had gained 20 kg in 3 years, diet and exercise was suggested.…”

Section: Resultsmentioning

confidence: 99%

Ovarian masses in infant-juvenile age

Sönmez

Türkyılmaz

Karabulut

et al. 2018

Arch Argent Pediatr

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Introduction.The appropraite surgical treatment to pediatric patients with ovarian lesions are heterogeneous and ovarian preservation is desirable in children. The aim of this study is to the discuss findings related to a set of patients who were operated on for ovarian lesions. Patients and methods. A retrospective study carried out in 13 years on 56 patients under the age of 17. These patients were divided into 3 groups according to ovarian pathologic diagnosis: 25 with functional (cyts and torsion), 18 with epithelial ovarian lesions and 13 with germ cell tumours. These three groups were compared in terms of menarche, torsion, age, duration, size, pain, mass, vomiting, irregular menstruation, location and operation type. Results. Follicle cysts, serous cyst adenomas and teratomas were the most common in these groups. The mean age of the patients was 12.18±4.84 years. The most common symptoms and signs were abdominal-pelvic pain (85.7%) and swelling(37.5%). Torsion was seen in 21 patients (37.5%), mean mass size was found to be 10.46±6.55 cm. A salpingo-oophorectomy (SO) was performed in 38 patients and cyst excision (CE) was performed in 18 patients. In premenarcheal cases, torsion was seen more in menarcheal cases and in the functional lesion group. CE was performed more often in the functional and t SO was performed often in the epithelial and germ cells groups. Conclusion. Torsion and functional ovarian pathologies are thought to be common in premenstrual ages and malign lesions are very rare in all age groups so we recommend ovarian protective surgery should be preferred.

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Section: Resultsmentioning

confidence: 99%

Ovarian masses in infant-juvenile age

Sönmez

Türkyılmaz

Karabulut

et al. 2018

Arch Argent Pediatr

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“…In summary, the serum levels of biomarkers cannot be used as the only available criterion for making a clinical decision. [23,24]. Serum Ferritin (SF) can be used as a prognostic biomarker…”

Section: Discussionmentioning

confidence: 99%

Association of Positive Results of Single Serum Biomarker with the Clinical Parameters

Luo

et al. 2019

BJSTR

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Background: Many serum biomarkers have been developed to diagnose cancers at an early stage and monitor drug therapy. At present, the most common clinical used serumtumor biomarkers are mainly including Alpha-Fetoprotein (AFP), Carcinoembryonic Antigen (CEA), Neurone Specific Enolase (NSE), Total Prostate Specific Antigen (TPSA), Human Epididymis Secretory Protein 4 (HE4), Carbohydrate Antigen 125 (CA125), CA153, CA19-9, CA72-4 and Serum Ferritin (SF). However, more and more studies have shown that serum markers were poor specific and sensitive in cancer early diagnosis, even among the most correlative cancers. Methods:In this work, we screened out and statistically analysed the relationship of the positive results and its distribution for all mentioned above serum biomarkers with the clinical parameters including patient's gender, age and disease types. Results:We found that most single serum biomarker had relatively low association with cancer, even for the most correlative cancer. we also found that the clinical diagnosis corresponding to single biomarker with high serum levels were various in addition to the diagnosis, treatment and prognosis of the most correlative cancer. Besides, there were no direct relationships of certain serum levels of the biomarkers with the type of disease. Conclusion:In summary, the serum levels of biomarkers cannot be used as the only available criterion for making a clinical decision. [23,24]. Serum Ferritin (SF) can be used as a prognostic biomarker

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“…El marcador CA 72-4 es específico de los tumores gastrointestinales y mamarios, pero se eleva después de tumores ováricos metastásicos y recurrentes. 10 En otro centro, se realizó un seguimiento de otro caso interesante por obesidad y aumento excesivo de peso en una paciente de 16 años. Debido a que la paciente había subido 20 kg en 3 años, se sugirió dieta y ejercicio.…”

Section: Quiste Del Cuerpo Lúteounclassified

Tumores ováricos en niñas y adolescentes

2018

Arch Argent Pediatr

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RESUMENIntroducción. El tratamiento quirúrgico adecuado para las pacientes pediátricas con lesiones ováricas es heterogéneo, y en las niñas es conveniente conservar los ovarios. El objetivo de este estudio es analizar los hallazgos relacionados con un grupo de pacientes a las que se operó por lesiones ováricas. Pacientes y métodos. Un estudio retrospectivo realizado durante 13 años con 56 pacientes menores de 17 años. Estas pacientes se dividieron en 3 grupos según el diagnóstico de patología ovárica: 25 tenían lesiones funcionales (quistes y torsión), 18 tenían lesiones ováricas epiteliales y 13 tenían tumores germinales. Se comparó a estos tres grupos en términos de menarquia, torsión, edad, duración, tamaño, dolor, tumor, vómitos, menstruación irregular, ubicación y tipo de operación. Resultados. En estos grupos, fueron más frecuentes los quistes foliculares, los cistoadenomas serosos y los teratomas. La media de edad de las pacientes fue de 12,18 ± 4,84 años. Los síntomas y signos más frecuentes fueron dolor (85,7%) e hinchazón (37,5%) en la región abdominopélvica. Se observó torsión en 21 pacientes (37,5%); la media del tamaño del tumor fue de 10,46 ± 6,55 cm. Se realizó una salpingoovariectomía (SO, por sus siglas en inglés) en 38 pacientes y una resección del quiste (CE, por sus siglas en inglés) en 18 pacientes. Se observaron más casos de torsión en las pacientes premenárquicas que en las menárquicas y en el grupo de lesiones funcionales. Se realizaron más resecciones quirúrgicas en el grupo de lesiones funcionales, y más SO en los grupos de lesiones epiteliales y tumores germinales. Conclusión. Se considera que la torsión y las patologías ováricas funcionales son frecuentes en la edad premenstrual, y las lesiones malignas son muy raras en todos los grupos etarios, por lo que se recomienda preservar la fertilidad en la cirugía. Palabras clave: neoplasias ováricas, tumor benigno, tumor maligno, cirugía, niña.

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Evaluation of tumor marker cancer antigen 72-4 (CA 72-4) in the monitoring of metastatic or recurrent tumors of the gastrointestinal tract, lung, breast, and ovaries.

Cited by 8 publications

References 0 publications

Ovarian masses in infant-juvenile age

Ovarian masses in infant-juvenile age

Association of Positive Results of Single Serum Biomarker with the Clinical Parameters

Tumores ováricos en niñas y adolescentes

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