The article considers the important problem of technical and economic optimization of the operating modes of the first rise section of water supply systems. At the same time, the task is to minimize the costs associated with the excessive operation of pumps, while providing the protection of the pipeline from freezing in harsh natural operating conditions. To solve this problem, a computer simulation model was developed for the first rise section, equipped with a pump performance control system. The main differences of the developed model are: integrated approach to the analysis of parameters of various physical nature, assessment of the object economic indicators, possibility of simulating non-standard control algorithms. Preliminary studies of the model have shown the possibility and feasibility of its application for calculating the optimal parameters and operating modes of the object under consideration. Based on the simulation results, it was revealed that to calculate the control action by level, it is advisable to use the PID law, for temperature—PD law, for flow rate—PI law. To calculate the main control action, it is proposed to simultaneously calculate the actions in terms of level and temperature, followed by bringing the larger of them to the value of the setpoint for the flow rate maintained by the flow controller. The studies of the proposed management concept for the first rise section have shown its high technical and economic efficiency. In particular, the savings in electricity consumption are estimated at about 55.2% while providing pipeline frost protection.