In this paper, the attitude-orbit coupled control problem for multi-spacecraft formation with limited communication capability and actuator failure is investigated. For the purpose of solving this problem, an event-triggered attitude-orbit coupled fault-tolerant control strategy is proposed. First, an integrated nonlinear dynamic model including the coupling characteristics of the attitude and orbit is established based on the Kane equation. Second, the nonlinear dynamic model is linearized at the reference state to facilitate the controller design. Third, a dynamic event-triggered mechanism is designed and an event-triggered fault-tolerant control law is developed. The stability of closed-loop control systems can be ensured under the designed control law and a sufficient condition that Zeno’s behavior can be avoided is presented. Finally, simulation results are given to show the effectiveness of the proposed control method.