Evidence based case report: Sore throat: diagnostic and therapeutic dilemmas

Graham, Anna R.; Fahey, Tom

doi:10.1136/bmj.319.7203.173

Cited by 14 publications

(11 citation statements)

References 10 publications

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“…9 Little concluded that, in patients with four sore throats (sic) a year who do not undergo tonsillectomy, two and a half days of sore throat are likely in the next six months; in the long term, this represents five days per year indefinitely. 11,12 While 90 per cent of patients are well one week after the onset of a sore throat, with or without antibiotics, this fails to address the group with true bacterial tonsillitis. This is analogous to undergoing an appendicectomy; it is impossible to have another episode of appendicitis thereafter.…”

Section: Discussionmentioning

confidence: 99%

Paediatric tonsillectomy: parental experience and outcomes

et al. 2008

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Section: Discussionmentioning

confidence: 99%

Paediatric tonsillectomy: parental experience and outcomes

et al. 2008

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“…January 28, 1999;EMEA/HMPWP/23/99 draft. ler et al, 1998;Graham and Fahey, 1999). Recovery, however, is little influenced by antibiotic use (Little et al, 1997a).…”

Section: Discussionmentioning

confidence: 99%

“…On the contrary, reattendance to the clinic may even be higher following a coarse of prescribed antibiotics, as such prescriptions may "medicalize" a self-limiting disease (Little et al, 1997b). Additionally, the use of antibiotics is associated with sideeffects affecting the individual and the community (e.g., diarrhea, rashes, candidiasis, unplanned pregnancy secondary to oral contraceptive failure) (Graham and Fahey, 1999) as well as an increase in multiresistant bacterial strains attributed to antibiotic overprescription (Benrimoj, et al, 2001). Considering their impact on bacterial resistance, the use of antibiotics for sore throat is not without risks (Graham and Fahey, 1999).…”

Section: Discussionmentioning

confidence: 99%

Safety and Efficacy of a Traditional Herbal Medicine (Throat Coat^®) in Symptomatic Temporary Relief of Pain in Patients with Acute Pharyngitis: A Multicenter, Prospective, Randomized, Double-Blinded, Placebo-Controlled Study

Brinckmann¹,

Sigwart²,

Taylor³

2003

The Journal of Alternative and Complementary Medicine

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Compared to placebo, intensity of throat pain when swallowing was significantly reduced by Throat Coat in intention to treat and valid for efficacy analysis (VEA). Significant differences in change from baseline pain were observed at 5 min (p = 0.007), 10 min (p = 0.005), 15 minutes (p = 0.01), 20 minutes (p = 0.05), and 30 minutes (p = 0.04) after completion of the first dose (VEA analysis). There was a statistically significant improvement of SPID in the Throat Coat-treated group: Least square means +/- standard error of the means (SEM) of SPID were -16.5 +/- 13.9 in the placebo group and -43.8 +/- 11.9 in the Throat Coat-treated group (p = 0.012). TOTPAR was also significantly higher in the Throat Coat-treated group: Least square means +/- SEM of TOTPAR were 32.4 +/- 12.8 in the placebo group and 53.6 +/- 10.9 in the Throat Coat-treated group (p = 0.031). This study shows that Throat Coat is significantly superior to placebo and provided a rapid, temporary relief of sore throat pain in patients with pharyngitis.

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“…9,10 These tests have sensitivities between 70% and 90% [11][12][13][14][15] and do not distinguish between carriage state and acute infection. 16,3 Diagnosis and treatment are further complicated by the requirement of patient followup, which can be problematic particularly in unreliable patients 17 or when continuity of care is difficult to achieve, as in the emergency department (ED).…”

mentioning

confidence: 99%