Evidence‐Based Evaluation and Management of Chronic Urticaria in Children

Zitelli, Kristine B.; Cordoro, Kelly M.

doi:10.1111/j.1525-1470.2011.01518.x

Cited by 24 publications

(10 citation statements)

References 75 publications

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“…How should CSU be managed in children?. Several studies have assessed the efficacy of treatment in paediatric patients with chronic urticaria, and recommendations for adults have been extrapolated to children [7,9,110]. The treatment of choice is standard dosage of second-generation H 1 -antihistamines, according to the products' technical specifications.…”

Section: Management In Special Casesmentioning

confidence: 99%

Management of urticaria: not too complicated, not too simple

Ferrer

Bartra

Giménez‐Arnau

et al. 2015

Clin Experimental Allergy

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In spite of being an old disease and apparently easy to diagnose, chronic spontaneous urticaria (CSU) is still perceived as an uncontrollable and difficult to manage disease. The perception of the patient is that his/her condition is not well understood and that is suffering from a disorder with hidden causes that doctors are not able to tackle. Sometimes patients go through a number of clinicians until they found some CSU expert who is familiar with the disease. It is surprising that myths and believes with no scientific support still persist. Guidelines are not widely implemented, and recent tools to assess severity are infrequently used. European and American recent guidelines do not agree in several key points related to diagnosis and treatment, which further contributes to confusion. With the aim to clarify some aspects of the CSU picture, a group of allergists and dermatologists from the Spanish Dermatology and Allergy societies developed a Frequent Asked Questions leaflet that could facilitate physicians work in daily practice and contribute to a better knowledge of common clinical scenarios related to patients with CSU.

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Section: Management In Special Casesmentioning

confidence: 99%

Management of urticaria: not too complicated, not too simple

Ferrer

Bartra

Giménez‐Arnau

et al. 2015

Clin Experimental Allergy

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“…One of the strengths of this study is the number of participants with a clearly defined diagnosis of CSU in the pediatric age group. Chronic urticaria is generally an uncommon disease in children which might affect up to 3% of a population according to epidemiologic studies . Its prevalence is rarer in this age group compared with the prevalence in adults .…”

Section: Discussionmentioning

confidence: 99%

Challenge-proven aspirin hypersensitivity in children with chronic spontaneous urticaria

Cavkaytar

Yılmaz

Büyüktiryaki

et al. 2015

Allergy

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“…When urticaria occurs without any trigger, it is classified as spontaneous. In childhood, stimuli such as infection, foods, and medication easily provoke acute urticaria [1]. Although most urticaria in children is inducible and acute, some urticaria are spontaneous and some become chronic.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of the H2-receptor antagonist famotidine on chronic spontaneous urticaria in children

Takatsuka¹,

Sakurai²,

Takada³

et al. 2013

OJPed

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Urticaria is a common pediatric skin disorder. Histamine H1-receptor antagonists are effective in chronic as well as acute urticaria. When H1-anti-histamines are ineffective, add-on use of H2-receptor antagonists is thought to give better symptom relief. However, there are few reports on the therapeutic efficacy in pediatric patients. We retrospectively reviewed the medical records of pediatric patients with chronic spontaneous urticaria (csU) who met the following criteria. They were consulted our outpatient clinic between April 2010 and March 2012; were unsuccessfully treated with H1 antihistamines; and were treated with add-on H2-receptor antagonist (famotidine). In six patients who met the inclusion criteria (mean age 6.1 ± 5.1 years), urticaria activity score was significantly decreased from 4.3 ± 0.8 just before administration of famotidine to 1.3 ± 1.0 on the first outpatient visit within 4 weeks after the first administration of famotidine (p < 0.0001). No adverse effects of famotidine were observed. Although this study has a limitation of small subjects, our results suggest the potential efficacy of add-on use of H2-receptor antagonists and might justify extending the range of application of H2-receptor antagonists to pediatric patients with csU.

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Evidence‐Based Evaluation and Management of Chronic Urticaria in Children

Cited by 24 publications

References 75 publications

Management of urticaria: not too complicated, not too simple

Management of urticaria: not too complicated, not too simple

Challenge-proven aspirin hypersensitivity in children with chronic spontaneous urticaria

Efficacy of the H2-receptor antagonist famotidine on chronic spontaneous urticaria in children

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