Evidence-Based Risk Factors for Seroma Formation in Breast Surgery

Kuroi, Katsumasa; Shimozuma, Kojiro; Taguchi, Tetsuya; Imai, Hirohisa; Yamashiro, Hiroyasu; Ohsumi, Shozo; Saito, Shinya

doi:10.1093/jjco/hyl019

Cited by 158 publications

(135 citation statements)

References 55 publications

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“…These findings correlate with the study done by Ackroyd et al and Bonnema et al that revealed no correlation between seroma formation and the total amount of drained serous fluid [24,33]. In contrast, Katsumasa et al had reported a positive association between seroma formation and drainage volume during the initial three postoperative days [34]. Also, Tadych et al found a significant relationship between the total hospital drain output and the frequency of seroma after modified radical mastectomy [3].…”

Section: Archives Of Clinical and Experimental Surgerysupporting

confidence: 85%

Closure of dead space after modified radical mastectomy: Does it reduce the incidence of seroma?

Abdelkader¹

2018

Arch Clin Exp Surg

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Section: Archives Of Clinical and Experimental Surgerysupporting

confidence: 85%

Closure of dead space after modified radical mastectomy: Does it reduce the incidence of seroma?

Abdelkader¹

2018

Arch Clin Exp Surg

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“…The reported incidence of seroma formation varies widely between 15 and 18% [2]. There are several factors implicated in seroma formation like the extent of lymph node clearance, number of positive nodes, the use of postoperative radiation and whether intraoperative lymphatic channel ligation was done or not, but opinion differs as to their individual role in its pathogenesis [2,3]. The main pathophysiology of seroma is still poorly understood and remains controversial.…”

Section: Introductionmentioning

confidence: 99%

Seroma Formation after Mastectomy: Pathogenesis and Prevention

Sampathraju

Rodrigues

2010

Indian J Surg Oncol

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Post mastectomy seroma remains an unresolved quandary as the risk factors for its formation have still not been identified. Seromas of the axillary space following breast surgery can lead to significant morbidity and delay in the initiation of adjuvant therapy. Various techniques and their modifications have been practiced and published in English literature, but there seems to be no consensus. In this article, all aspects of seroma formation from pathogenesis to prevention including drug therapies have been discussed.

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“…However, there is evidence showing that sentinel lymph node biopsy reduces seroma formation. 17 The study conducted by van Heurn and brink in 1995 on 40 patients concluded that low vacuum drains were removed earlier than high vacuum drains. However, seroma production was not significantly different between the two groups.…”

Section: Discussionmentioning

confidence: 99%

Active versus passive drainage after modified radical mastectomy in breast cancer

Oommen¹,

Augustine²,

Gopi³

2018

Int Surg J

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INTRODUCTIONWorldwide, breast cancer is the leading type of cancer in women, accounting for 25% of all cases.1 In those who have been diagnosed with cancer, a number of treatments may be used, including surgery, radiation therapy, chemotherapy, hormonal therapy and targeted therapy. Surgical intervention ranges from wide local excisions to palliative mastectomy.Modified Radical Mastectomy involves removal of the entire breast including the breast tissue, skin, areola, nipple and most of the axillary lymph nodes.Outcomes for breast cancer vary depending on the cancer type, extent of disease, and person's age. Survival rates in the developed world are high, with between 80% and 90% of those in England and the United States alive for at least 5 years.2 In developing countries survival rates are poorer. Drains remove blood, serum, lymph, and other fluids that accumulate in the wound bed after a procedure. If allowed to build, these fluids put pressure on the surgical site as well as adjacent organs, vessels, and nerves. The decreased perfusion delays healing and the increased pressure causes pain. In addition, fluid collection serves ABSTRACT Background: Active drains are routinely used after Modified Radical Mastectomy (MRM) and is an important factor contributing to increased hospital stay as the patients are often discharged only after their removal. Amongst various factors that influence the amount of post operative drainage, the negative suction pressure applied to the drain has been reported to be of great significance. Against this background a study was conducted to compare the amount and duration of drainage between suction and dependent drainage in patients following Modified Radical Mastectomy. Methods: Patients were randomised using randomly ordered sealed envelopes, which were opened immediately before the closure of the wound, to decide on whether suction or dependent drain was to be given. Drains were removed when output was less than 30 ml per day. Patients were followed up from the day of surgery till the day of drain removal. Statistical analysis was performed with SPSS. Results: There is significant increase in the drain per day in post MRM patients with active suction drain. But, there is no relation between the type of drain and either total drain output or the total number of days of drain. The study also revealed that there is no significant difference in the number of days of hospital stay in both groups of patients. Conclusions: Suction drains do not have any significant advantage over dependent drains after Modified Radical Mastectomy in breast cancer patients.

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Evidence-Based Risk Factors for Seroma Formation in Breast Surgery

Abstract: Although a number of factors have been correlated with seroma formation, strong evidence is still scarce. However, there is evidence showing that sentinel lymph node biopsy reduces seroma formation.

Cited by 158 publications

References 55 publications

Closure of dead space after modified radical mastectomy: Does it reduce the incidence of seroma?

Closure of dead space after modified radical mastectomy: Does it reduce the incidence of seroma?

Seroma Formation after Mastectomy: Pathogenesis and Prevention

Active versus passive drainage after modified radical mastectomy in breast cancer

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