Evolución de 10 años de aplicación de la ventilación mecánica en la insuficiencia respiratoria aguda del paciente hematológico ingresado en la unidad de cuidados intensivos

Muncharaz, A. Belenguer; Albert-Rodrigo, L.; Ferrándiz-Sellés, Amparo; Cebrián-Graullera, G.

doi:10.1016/j.medin.2012.12.011

Cited by 21 publications

(15 citation statements)

References 35 publications

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“…All included studies compared NIV with IMV as the first mechanical ventilation technique in immunocompromised patients with ARF. Settings in the NIV group were as follows: (1) Ventilation modes: two studies [27, 32] used continuous positive airway pressure (CPAP) ventilation only; three [33, 34, 36] solely used bilevel positive airway pressure (BiPAP); another five [17, 20, 28, 30, 37] solely used pressure support ventilation (PSV); another one [31] used both CPAP and Bi-PAP; no description was given in the remaining studies. (2) Interfaces: full face mask, face mask, nasal mask or helmet.…”

Section: Resultsmentioning

confidence: 99%

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Noninvasive versus invasive mechanical ventilation for immunocompromised patients with acute respiratory failure: a systematic review and meta-analysis

et al. 2016

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BackgroundTo determine the effects of noninvasive mechanical ventilation (NIV) compared with invasive mechanical ventilation (IMV) as the initial mechanical ventilation on clinical outcomes when used for treatment of acute respiratory failure (ARF) in immunocompromised patients.MethodsWe searched PubMed, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), the Chinese Biomedical Literature Database (CBM) and other databases. Subgroup analyses by disease severity and causes of immunodeficiency were also conducted.ResultsThirteen observational studies with a total of 2552 patients were included. Compared to IMV, NIV was shown to significantly reduce in-hospital mortality (OR 0.43, 95 % CI 0.23 to 0.80, P value = 0.007) and 30-day mortality (OR 0.34, 95 % CI 0.20 to 0.61, P value < 0.0001) in overall analysis. Subgroup analysis showed NIV had great advantage over IMV for less severe, AIDS, BMT and hematological malignancies patients in reducing mortality and duration of ICU stay.ConclusionsThe overall evidence we obtained shows NIV does more benefits or at least no harm to ARF patients with certain causes of immunodeficiency or who are less severe.Electronic supplementary materialThe online version of this article (doi:10.1186/s12890-016-0289-y) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

“…Another (Gristina 2011) [17] reported that the mean duration of mechanical ventilation was 4 days (SD 4 days) in NIV group, compared to 11 days (SD 4 days) in IMV group ( P value < 0.0001). The rest (B-M 2013) [36] revealed no difference among the two groups ( P value = 0.08).…”

Section: Resultsmentioning

confidence: 99%

Noninvasive versus invasive mechanical ventilation for immunocompromised patients with acute respiratory failure: a systematic review and meta-analysis

et al. 2016

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“…Intra-ICU mortality in those patients who were successfully managed with NIMV was 22%; whereas in those requiring intubation,the mortality rate was 60% (58% in those initially submitted to IMV and 72% in those intubated after NIMV failure). Only two studies (5,14) reported the causes of death, infection, septic shock, and multiorgan failure as being the most frequent.…”

Section: Initial Ventilatory Strategy and Outcomesmentioning

confidence: 99%

“…Invasive ventilatory support (requiring intubation), while improving gas exchange, has been related to a high mortality rate (4). On the contrary, the use of noninvasive ventilation has been associated with better outcomes (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17). However, this strategy shows a high failure rate, requiring intubation (18).…”

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confidence: 99%

Impact of Initial Ventilatory Strategy in Hematological Patients With Acute Respiratory Failure: A Systematic Review and Meta-Analysis*

Amado-Rodríguez

Bernal

López-Alonso

et al. 2016

Critical Care Medicine

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“…[1] Despite significant advances in treatment strategies for critically ill patients in the ICU, the mortality rate of ARF remains high. [2] Specific diseases or conditions affecting ICU outcomes are well studied, i.e., solid or hematological malignancies, neurological diseases, obesity, septic shock, and renal failure, [3][4][5] and chronic obstructive pulmonary disease (COPD) is known to account for the majority of ICU admissions and mortality due to ARF. Cardiovascular diseases, hypertension, osteoporosis, depression, diabetes mellitus (DM), and lung cancer are reported as COPD-related comorbidities.…”

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confidence: 99%

Intensive Care Unit and 12-month Mortality of Patients with Acute Respiratory Failure Admitted to the Intensive Care Unit: What is the Role of Comorbidities?

Takır

2019

EJMO

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A cute respiratory failure (ARF) is a leading cause of intensive care unit (ICU) admission and both short-and long-term mortalities. [1] Despite significant advances in treatment strategies for critically ill patients in the ICU, the mortality rate of ARF remains high. [2] Specific diseases or conditions affecting ICU outcomes are well studied, i.e., solid or hematological malignancies, neurological diseases, obesity, septic shock, and renal failure, [3][4][5] and chronic obstructive pulmonary disease (COPD) is known to account for the majority of ICU admissions and mortality due to ARF. Cardiovascular diseases, hypertension, osteoporosis, depression, diabetes mellitus (DM), and lung cancer are reported as COPD-related comorbidities. [6] A recent study investigated COPD as a cause of ICU admission and a co-Objectives: There are limited data regarding the effect of comorbidities in the intensive care unit (ICU) and 12-month mortality rates of patients with acute respiratory failure (ARF) who are admitted to the ICU. The present investigation was designed to determine the effect of comorbidities and identify long-term mortality predictors in this patient group. Methods: A retrospective observational cohort study was performed in a 22-bed, tertiary ICU in a teaching and research hospital. All patients who were admitted to the ICU during 2012 were included in the study. Demographics, comorbidities, ICU data at the time of admission, and the last control were recorded. ICU mortality and 12-month mortality after ICU discharge were analyzed by Cox regression and Kaplan-Meier survival analysis. Results: During the study period, 1022 patients (362 females) were admitted to the ICU, and the ICU mortality was 20.8%. Older age, non-invasive mechanical ventilation failure, more invasive mechanical ventilation days, tachycardia, Acute Physiological and Chronic Health Evaluation (APACHE II) score at the time of admission, low albumin, and the ratio of partial arterial oxygen pressure to inspired fractionated oxygen were associated with increased mortality. Interestingly, the presence of chronic obstructive pulmonary disease (COPD) was associated with decreased mortality. The 12-month mortality rate of the 809 patients who were discharged from the ICU was 51.9% (n = 420). Half of these patients died within the first 2 months after discharge. Cancer, low albumin, and higher APACHE II score at the time of discharge were identified as mortality risk factors. Conclusion: Patients with ARF who are admitted to the ICU have a higher rate of mortality, and only half survive >1 year after discharge. COPD is a comorbid disease associated with an increased likelihood of long-term survival, whereas malignancy is associated with poor prognosis after ICU discharge.

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Evolución de 10 años de aplicación de la ventilación mecánica en la insuficiencia respiratoria aguda del paciente hematológico ingresado en la unidad de cuidados intensivos

Cited by 21 publications

References 35 publications

Noninvasive versus invasive mechanical ventilation for immunocompromised patients with acute respiratory failure: a systematic review and meta-analysis

Noninvasive versus invasive mechanical ventilation for immunocompromised patients with acute respiratory failure: a systematic review and meta-analysis

Impact of Initial Ventilatory Strategy in Hematological Patients With Acute Respiratory Failure: A Systematic Review and Meta-Analysis*

Intensive Care Unit and 12-month Mortality of Patients with Acute Respiratory Failure Admitted to the Intensive Care Unit: What is the Role of Comorbidities?

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