Evolution of Lipid Profile, Liver Function, and Pattern of Plasma Fatty Acids According to the Type of Lipid Emulsion Administered in Parenteral Nutrition in the Early Postoperative Period After Digestive Surgery

Abstract

All ILEs administered were safe and well tolerated. The changes in serum fatty acids reflected the pattern of fatty acids administered with different ILEs. The group receiving the olive oil emulsion achieved a fatty acid composition of serum lipids that could offer major therapeutic or biological advantages.

Alternative lipid emulsions in the critically ill: a systematic review of the evidence

“…Of these, we excluded 40 trials due to the following reasons: 22 trials [14,15,16,17,18,19,20,21,22,23,24,25,26,27, 28,29,30,31,32,33,34,35] trials did not include ICU patients (mostly elective surgery and cancer patients), 12 trials [36,37,38,39,40,41,42,43,44,45,46,47] did not evaluate clinically important outcomes; 2 trials [48,49] did not include SO-based LE in the control group; 1 trial [50] compared LCT vs. another LCT emulsion without reduction in SO; 1 trial [51] was conducted in a pediatric population; 1 trial[52] had a short duration of intervention (12 hour of lipid emulsion infusion during the first day); 1 trial included patients with poisoning and not representative of ICU patients[53]. In the end, 12 RCTs [54,55,56,57,58,59,60,61,62,63,64,65] enrolling a total of 806 patients met the inclusion criteria and were included in this systematic review (see Table 1 and 2).…”

Parenteral Beslenen Yoğun Bakım Hastalarında Soya Yağı, Zeytinyağı ve Mct-Lct Bazlı Nutrisyon Solüsyonlarının Etkilerinin Karşılaştırılması

“…Uzun süreli (4 haftaya kadar) TPN izlemi yapılan hastaların %3,6'sında bazal değere göre INR'de yükselme saptanmıştır. Tüm yükselmeler çok az ve hiçbir hastada klinik olarak kanama görülmemiştir (31 (37). Çalışmamızda her 3 grup arasında lipid profilleri karşılaştırıldığında istatistiksel olarak anlamlı farklılık gözlenmedi.…”

Intravenous fat emulsion in clinical practice: Nutrient and antidote

“…This made IVFEs an important part of total parenteral nutrition regimens 3,4 . These acids cannot be synthesized in the body, and they are important to maintain the normal composition of the structural body lipids, as well as in the synthesis of the various important metabolic mediators 6 . These acids cannot be synthesized in the body, and they are important to maintain the normal composition of the structural body lipids, as well as in the synthesis of the various important metabolic mediators 6 .…”