The effects of prior cold deformation on the microstructures and the room temperature mechanical properties of an Al-3 . 5Cu-1 . 5Li-0 . 22(SczZr) alloy have been observed by using TEM and tensile test at room temperature. The results show that the alloy has the character of aging hardening, and the major phase of precipitation and strengthening is T 1 phase. The result also show that prior cold deformation leads to more dispersive and uniform distribution of T 1 precipitations. It accelerates aging response, causes earlier aging peak occurrence, and enhances strength greatly. However, the plasticity of the alloy is declined with prior cold deformation. In contrast, excessive prior cold deformation causes coarsening and heterogeneous distribution of T 1 phase. It also reduces the strength of the alloy, therefore, influences the composite properties of the alloy. The favourable prior cold deformation is about 3 . 5% under the experimental condition.