Evolution of thioester-containing proteins revealed by cloning and characterization of their genes from a cnidarian sea anemone, Haliplanella lineate

Fujito, Naoko T.; Sugimoto, Sanae; Nonaka, Masaru

doi:10.1016/j.dci.2010.02.011

Cited by 58 publications

(48 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Two copies of C3-like genes have also been described in the anemones N. vectensis (Kimura et al 2009) and Haliplanella lineata (Fujito et al 2010), and a phylogenetic analysis of TEPs suggested that a duplication of the C3-like gene occurred in the common ancestor of anthozoans (corals and tube-dwelling anemones) (Fig. 6).…”

Section: The P Strigosa Immune Signal Transduction Modulementioning

confidence: 94%

“…The Bf, MASP, and If complement families have in common the presence of a serine protease trypsin-like domain, whereas the C6 family contains a membrane-attack complex/ perforin (MAC/PF) domain. Complement-encoding genes identified in cnidarians include those coding for C3, factor B (Bf), and mannose-binding lectin (MBL)-associated serine proteases (MASP) (Dishaw et al 2005;Fujito et al 2010;Kenkel et al 2011;Kimura et al 2009;Miller et al 2007). The phenoloxidase system participates actively in the immune response of various invertebrate taxa (Cerenius et al 2008).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The immunotranscriptome of the Caribbean reef-building coral Pseudodiploria strigosa

Ocampo

Zárate-Potes

Pizarro³

et al. 2015

Immunogenetics

View full text Add to dashboard Cite

The viability of coral reefs worldwide has been seriously compromised in the last few decades due in part to the emergence of coral diseases of infectious nature. Despite important efforts to understand the etiology and the contribution of environmental factors associated to coral diseases, the mechanisms of immune response in corals are just beginning to be studied systematically. In this study, we analyzed the set of conserved immune response genes of the Caribbean reef-building coral Pseudodiploria strigosa by Illumina-based transcriptome sequencing and annotation of healthy colonies challenged with whole live Gram-positive and Gram-negative bacteria. Searching the annotated transcriptome with immune-related terms yielded a total of 2782 transcripts predicted to encode conserved immune-related proteins that were classified into three modules: (a) the immune recognition module, containing a wide diversity of putative pattern recognition receptors including leucine-rich repeat-containing proteins, immunoglobulin superfamily receptors, representatives of various lectin families, and scavenger receptors; (b) the intracellular signaling module, containing components from the Toll-like receptor, transforming growth factor, MAPK, and apoptosis signaling pathways; and (3) the effector module, including the C3 and factor B complement components, a variety of proteases and protease inhibitors, and the melanization-inducing phenoloxidase. P. strigosa displays a highly variable and diverse immune recognition repertoire that has likely contributed to its resilience to coral diseases.

show abstract

Section: The P Strigosa Immune Signal Transduction Modulementioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

The immunotranscriptome of the Caribbean reef-building coral Pseudodiploria strigosa

Ocampo

Zárate-Potes

Pizarro³

et al. 2015

Immunogenetics

View full text Add to dashboard Cite

show abstract

“…However, no TEP gene is present in the published genome information for a sponge, Amphimedon queenslandica [8] and a choanoflagellate, Monosiga brevicollis [9], suggesting that this gene family arose in the eumetazoan lineage. The three types of TEP genes, C3, A2M and CD109 were identified in two cnidarian sea anemones, Haliplanella lineate [10] and Nematostella vectensis [11,12], indicating that differentiation of the TEP genes into C3, A2M and CD109 had completed before the divergence of cnidaria and bilateria. All deuterostome species analyzed thus far such as various vertebrates, urochordate sea squirt [13], cephalochordate lancelet and echinoderm sea urchin [2], possess both the C3 and A2M family members, whereas many protostome genomes deciphered thus far such as fly [14], mosquito [15], honeybee [16], parasitoid wasp [17], aphid [18], flour beetle [19], and Caenorhabditis elegans [20] possessed only the A2M family members.…”

Section: Evolution Of the Tep Superfamilymentioning

confidence: 98%

Evolution of the Complement System

Nonaka

2014

Subcellular Biochemistry

Self Cite

113

View full text Add to dashboard Cite

The mammalian complement system constitutes a highly sophisticated body defense machinery comprising more than 30 components. Research into the evolutionary origin of the complement system has identified a primitive version composed of the central component C3 and two activation proteases Bf and MASP in cnidaria. This suggests that the complement system was established in the common ancestor of eumetazoa more than 500 million years ago. The original activation mechanism of the original complement system is believed to be close to the mammalian lectin and alternative activation pathways, and its main role seems to be opsonization and induction of inflammation. This primitive complement system has been retained by most deuterostomes without major change until the appearance of jawed vertebrates. At this stage, duplication of the C3, Bf and MASP genes as well as recruitment of membrane attack components added the classical and lytic pathways to the primitive complement system, converting it to the modern complement system. In contrast, the complement system was lost multiple times independently in the protostome lineage.

show abstract

“…As a central component in the complement system, component 3 is an intermediary between the innate and the adaptive immune systems [40,41]. During the past few years, the homologs of C3 have been identified, from higher vertebrates to lower protostomes including human, fish, amphioxus, sea squirt, sea urchin, horseshoe crab, coral, and sea anemone [42][43][44]. Past studies have shown that there are analogs of complement in Asterias forbesi, and in its coelomic cells there were C3b and C3bi complement receptors [45,46].…”

Section: Immune Responsementioning

confidence: 99%

Synergy of microcapsule polysaccharides and Bacillus subtilis on the growth, immunity and resistance of sea cucumber Apostichopus japonicus against Vibrio splendidus infection

Fan

et al. 2013

Fish Sci

View full text Add to dashboard Cite

A 4-week feeding trial was conducted to determine the effects of different dietary supplements on the growth, immunity and resistance of sea cucumber Apostichopus japonicus against Vibrio splendidus infection. The control group was supplied with blank microcapsules, and Astragalus polysaccharide (APS) microcapsules, tuckahoe polysaccharide (TPS) microcapsules, (APS ? TPS) microcapsules, (APS ? TPS) microcapsules ? Bacillus subtilis, were tested for effects. Coelomic fluid was collected at 7-day intervals to test activities of lysozyme (LSZ), superoxide dismutase (SOD), alkaline phosphatase (AKP), and complement 3 (C3) content. After the feeding trial, the specific growth rate of sea cucumbers fed a diet supplemented with (APS ? TPS) microcapsules ? B. subtilis was significantly increased (P \ 0.05); activities of LSZ, SOD, AKP and C3 content were significantly higher than in other groups (P \ 0.05). The challenge test showed that the cumulative mortality of sea cucumbers fed a diet supplemented with (APS ? TPS) microcapsules ? B. subtilis reduced significantly (P \ 0.05). In conclusion, dietary combinations of (APS ? TPS) microcapsules ? B. subtilis has a potential for use in diet formulations for sea cucumbers to significantly increase growth, immunity and disease resistance against V. splendidus infection.

show abstract

Evolution of thioester-containing proteins revealed by cloning and characterization of their genes from a cnidarian sea anemone, Haliplanella lineate

Cited by 58 publications

References 23 publications

The immunotranscriptome of the Caribbean reef-building coral Pseudodiploria strigosa

The immunotranscriptome of the Caribbean reef-building coral Pseudodiploria strigosa

Evolution of the Complement System

Synergy of microcapsule polysaccharides and Bacillus subtilis on the growth, immunity and resistance of sea cucumber Apostichopus japonicus against Vibrio splendidus infection

Contact Info

Product

Resources

About