Ewing's Sarcoma: Dural Metastases after Intracranial Hemorrhage

Öz, İbrahim İlker; Şerifoğlu, İsmail; Oz, Evrim Bozay; Pişkin, Etem; Edebali, Nurullah

doi:10.1159/000369352

Cited by 3 publications

(3 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As stated by Rana et al and Valdes et al [27,28] distant metastasis usually involves the lung (38%), bone (including the spine; 31%) and the bone marrow of cases, only a few cases being reported in literature till date [29]. Dural metastases have also been described with ES in a very limited number of cases [30,31].…”

Section: Discussionmentioning

confidence: 99%

“…This technique also documents skull metastases, and the infiltrated dura, which is highly aggressive and therefore cannot be cured with surgery. Since scalp metastasis in ES may herald the diagnosis of internal malignancy in the head, with the present case we attempt to expose the additional diagnostic value of MRI to evaluate soft tissue involvement, particularly in patients with potential compromise of the central nervous system (CNS) [22,23].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Magnetic Resonance Imaging (MRI) of Metastatic Scalp, Skull and Dural Tumors in a Case of Ewing’s Sarcoma, with Literature Review

Isabel

2023

CTOIJ

View full text Add to dashboard Cite

The prognosis of patients with initially metastatic ES is very poor. Significant risk factors for death include affectation at combined local and distant sites and soft tissue involvement. For the diagnosis, an initial radiographic and/or computed tomography (CT) is performed. Both techniques are outstanding in evaluating the affected bones. However, when primary Ewing´s tumor or its metastases involves soft tissues, these might be misdiagnosed if magnetic resonance imaging (MRI) is not applied. The purpose of the present case is to expose the role of MRI in the assessment of a rare and aggressive ES with metastases affecting bones and soft tissue of the head.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Magnetic Resonance Imaging (MRI) of Metastatic Scalp, Skull and Dural Tumors in a Case of Ewing’s Sarcoma, with Literature Review

Isabel

2023

CTOIJ

View full text Add to dashboard Cite

show abstract

“…Skull metastases to petrous bone, cuneiform bone, parietal bone, frontal bone, and clivus associated with scalp involvement have been described in the literature [4,[7][8][9][10]. Dural metastases, though rare has also been described with ES by various authors [11,12]. Since metastases to skull bones is rarely seen with ES, it can be confused with other lesions like olfactory neuroblastoma as described by Gaba et al, [13].…”

Section: Discussionmentioning

confidence: 99%

Ewing’s Sarcoma Multifocal Metastases to Temporal and Occipital Bone: A Rare Presentation

Rana

Wadhwa

Bhargava

et al. 2015

JCDR

View full text Add to dashboard Cite

An 11-year-old male patient was referred to the ENT department at Lok Nayak Hospital with the complaints of right ear discharge, facial weakness, inability to close right eye, and a gradually progressive occipital swelling for one month. In addition, he complained of decreased hearing from right ear, as well as headache. The patient was a known case of Ewing's sarcoma of the left pelvic bones, with involvement of iliac bone, ischium and sacroiliac joint. He had presented initially with the complaints of pain in the left hip and a swelling in the groin and was started upon five cycles of multidrug chemotherapy that included ifosfamide, etoposide, vincristine, actinomycin-D and cyclophosphamide. This was followed by radiotherapy, with a total body dose of 55 Gy over 30 cycles. In view of persistent disease, patient further received 3 cycles of chemotherapy (CT) with ifosfamide, carboplatin and etoposide. It was during one of the follow up visits that patient complained of right sided ear discharge, facial weakness, and an occipital swelling, and was referred to ENT clinic for evaluation.On examination, patient had a red polypoidal mass in the right bony external auditory canal (EAC) with some overlying sero-sanguinous discharge on the floor. The mass was found to be extending into the middle ear, with disruption of lower part of tympanic membrane. It was friable and bled on probing. He also had right sided facial weakness with history of deviation of angle of mouth towards left, suggestive of a right sided lower motor neuron (LMN) type facial nerve palsy . However, patient's right eye was close at the time of examination due to conjuctival chemosis and oedema. The patient had an associated 6 x 6 cm swelling present over the ABSTRACTEwing's sarcoma (ES) is a common malignant bone tumour seen to involve long bones, flat pelvic bones and ribs and vertebrae in majority of cases. Here, we present a rare case of aggressive primary ES of pelvic bones with multifocal metastases to temporal bone and occipital bone. The patient presented with facial palsy and an occipital swelling, and was referred for chemotherapy.occipital bone [Table /Fig-1b]. The swelling was non tender, immobile, and hard in consistency. The overlying skin appeared stretched, and there were multiple dilated scalp veins over the swelling and the adjoining area.The patient underwent computed tomography scan of temporal bone and head revealing soft tissue attenuation contents in the right mastoid air cells and middle ear, with erosion of right ear ossicles, tegmen tympani and scutum [Table/ Fig-2a&b]. The facial canal was eroded at the genu and tympanic segment. Scans through the head revealed an isodense lesion involving occipital bone, heterogeneously enhancing after contrast administration. There was no brain involvement. The patient was taken up for biopsy of the mass which revealed fibro collagenous tissue infiltrated by small round cells, having high nucleus: cytoplasm ratio and few mitoses. The tumour cells were positive for vimentin, neuron speci...

show abstract

Primary Ewing’s Sarcoma affecting the Central Nervous System: A single-center experience and Narrative review

Kumarasamy,

Garg,

Singh

et al. 2024

Childs Nerv Syst

View full text Add to dashboard Cite

Ewing's Sarcoma: Dural Metastases after Intracranial Hemorrhage

Abstract: Ewing's sarcoma (ES) is a primary malignant tumor of the mesenchymal tissue of bone in children and young adults. Central nervous system metastases of ES are rarely seen. In this paper, we report a case of ES that progressed with dural metastases after spontaneous intracerebral hemorrhage.

Cited by 3 publications

References 11 publications

Magnetic Resonance Imaging (MRI) of Metastatic Scalp, Skull and Dural Tumors in a Case of Ewing’s Sarcoma, with Literature Review

Magnetic Resonance Imaging (MRI) of Metastatic Scalp, Skull and Dural Tumors in a Case of Ewing’s Sarcoma, with Literature Review

Ewing’s Sarcoma Multifocal Metastases to Temporal and Occipital Bone: A Rare Presentation

Primary Ewing’s Sarcoma affecting the Central Nervous System: A single-center experience and Narrative review

Contact Info

Product

Resources

About