Excessive bleeding after surgery in osteogenesis imperfecta

Orthognathic bimaxillary surgery in two patients with osteogenesis imperfecta and a review of the literature

“…There was some postoperative bleeding, as MORTON earlier reported 15 . Extubation was delayed until the next day.…”

“…Despite this, the patient had to be transfused with plasma and blood. Postoperatively, no abnormality was found in the haematological examinations except of a slightly raised international normalized ratio (INR) value 15 .…”

An unusual manifestation of bleeding diathesis in a patient with osteogenesis imperfecta

“…This osteogenesis imperfecta and there are several reports exact cause of DIC in this patient could not be identified, it is important to state that incompatibility of of excessive bruising [14-16] and of slow generalized transfused red cells was specifically excluded. Peoozing from wound sites following surgery [17,18]. It techial haemorrhage is not a manifestation of acute has been reported that up to two thirds of patients DIC.…”

“…a number of patients. Morton [18] reported excessive Bleeding diatheses of any aetiology may occur and this bleeding in a patient with osteogenesis imperfecta should be anticipated so that aggressive management who underwent Le Fort osteotomy; although that may be instituted early and avert fatality. patient reported bruising easily, no bleeding problems had occurred during previous surgery.…”

Radical prostatectomy in a patient with osteogenesis imperfecta: A possible surgical trap

“…In addition, the defect of collagen synthesis can cause excessive bruising and generalized oozing from wound sites. There is a 10 Á/30% incidence of bleeding diathesis, and individuals with OI have an increased risk of bleeding when undergoing surgery [7,8]. AP should be recognized on X-rays as it is specific for each type of OI [2].…”