Excitation Test of Superconducting Magnet in 230-MeV Isochronous Cyclotron for Proton Therapy

Yoshida, Jun; Hirabayashi, Masayuki; Hashimoto, Atsushi; Morie, Takaaki; Arakawa, Y.; Taki, Kazuya; Mitsubori, H.; Tsutsui, Hiroshi; Tsurudome, Takehisa; Mikami, Yukio

doi:10.1109/tasc.2019.2962675

Cited by 5 publications

(3 citation statements)

References 1 publication

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“…This type of cyclotron is today adopted in several commercial proton therapy systems, such as ProBeam system (Varian, Palo Alto, CA, United States) and the ProNova SC360 system (Pronova Solutions, Maryville, TN, United States). Conceptual designs of other compact superconducting isochronous cyclotrons for proton therapy are available, including a compact and lighter weight (65 tons) version by Sumitomo Heavy Industries Ltd (Ehime, Japan) [24], which is shown in Fig. 2.…”

Section: Cyclotronsmentioning

confidence: 99%

Technological Developments and Future Perspectives in Particle Therapy: A Topical Review

Kraan,

Del Guerra

2024

IEEE Trans. Radiat. Plasma Med. Sci.

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In the last decades, important technological progress has been made to enhance the quality and efficiency of particle therapy treatments. Continuous improvements in dose delivery, treatment planning and verification techniques have lead to higher dose conformity and better sparing of healthy tissue. At the same time, particle therapy treatments are complex and much more expensive than conventional radiotherapy, and only highly specialized facilities can offer these treatments. Cost reduction is thus a strong drive behind technological developments in the field. The number of treatment facilities offering proton and carbon therapy has strongly grown in the last decades, and the amount of research efforts and innovations have increased continuously.From a technological perspective, advances in hardware are often accompanied by innovations in software and computation, and vice versa. In this review we will present a basic overview of technological advances in particle therapy hardware (accelerators, gantries, applications of superconductivity, treatment verification techniques), software (Monte Carlo simulations, treatment planning calculations), and studies towards clinical applications. By combining a broad selection of topics into a single review and by covering both proton and carbon therapy, we aim at providing the reader a unique overview of the evolution of various technologies developed for particle therapy.

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Section: Cyclotronsmentioning

confidence: 99%

Technological Developments and Future Perspectives in Particle Therapy: A Topical Review

Kraan,

Del Guerra

2024

IEEE Trans. Radiat. Plasma Med. Sci.

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“…Proton therapies are increasingly used due to their unique dosimetric advantage in depositing the bulk of their dose under the Bragg peak near the end of their range 1 . Proton beams are generated using particle accelerators such as synchrotrons 2 or compact cyclotrons (synchrocyclotrons or isochronous cyclotrons) with the latter being increasingly used in single‐room proton facilities 3,4 . Compared to traditional passive scattering deliveries, pencil beam scanning (PBS) delivers a clinical proton plan by deflecting the focused proton beam magnetically to cover a large treatment volume, 5 and allows for the (a) creation of more conformal plans using advanced intensity‐modulated‐proton‐therapy (IMPT) techniques, 6 (b) irradiation at deeper depths and larger field sizes and (c) reduction of neutron doses by eliminating the need for lead scatterers and brass collimators 7,8 .…”

Section: Introductionmentioning

confidence: 99%

“…1 Proton beams are generated using particle accelerators such as synchrotrons 2 or compact cyclotrons (synchrocyclotrons or isochronous cyclotrons) with the latter being increasingly used in single-room proton facilities. 3,4 Compared to traditional passive scattering deliveries, pencil beam scanning (PBS) delivers a clinical proton plan by deflecting the focused proton beam magnetically to cover a large treatment volume, 5 and allows for the (a) creation of more conformal plans using advanced intensity-modulatedproton-therapy (IMPT) techniques, 6 (b) irradiation at deeper depths and larger field sizes and (c) reduction of neutron doses by eliminating the need for lead scatterers and brass collimators. 7,8 For cyclotrons, since the energy of the extracted beam is fixed, an energy selection system is needed in the beamline which consists of a degrader of variable thickness, for example, graphite, to intercept the proton beam.…”

Section: Introductionmentioning

confidence: 99%

Development of a storage phosphor imaging system for proton pencil beam spot profile determination

et al. 2021

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Purpose Accurate two‐dimensional (2D) profile measurements at submillimeter precision are necessary for proton beam commissioning and periodic quality assurance (QA) purposes and are currently performed at our institution with a commercial scintillation detector (Lynx PT) with limited means for independent checks. The purpose of this work was to create an independent dosimetry system consisting of an in‐house optical scanner and a BaFBrI:Eu2+ storage phosphor dosimeter by: (a) determining the optimal settings for the optical scanner, (b) measuring 2D proton spot profiles with the storage phosphors, and (c) comparing them to similar measurements using a commercial scintillation detector. Methods An in‐house 2D laboratory optical scanner was constructed and spatially calibrated for accurate 2D photostimulated luminescence (PSL) dosimetry. Square 5 × 5 cm2 BaFBrI:Eu2+ dosimeter samples were uniformly irradiated with line scans performed to determine the physical and electronic scanner settings resulting in the highest signal‐to‐noise ratios (SNR) at a sub‐millimeter spatial resolution. The resultant spatial resolution of the scanner was then quantitatively assessed by measuring (a) line pairs on a standard X‐ray lead bar phantom and (b) modulation transfer functions. Following this, 2D proton spot profiles from a Mevion S250i Hyperscan proton unit were obtained at 1, 10, 20, 30, 40, and 50 monitor unit (MU) settings at maximum energy (E0 = 227.1 MeV) and compared to baseline profiles from a commercial scintillation detector, where 1 MU is calibrated to deliver 1 Gy absolute proton dose‐to‐water under reference conditions, that is, 41 × 41 proton spots uniformly spaced by 0.25 cm within a 10 × 10 cm2 square field size at maximum energy (227.1 MeV) in water at depth of 5 cm at isocenter. The dosimetric system's sensitivities to (a) ±1 mm positional shifts and (b) ±0.3 mm beam lateral spread changes were quantitatively evaluated through a Gaussian fitting of the crossline and inline plots of the respective artificially shifted beam profiles. Results The physical scanner settings of (a) Δτ = 27 ms time interval between data samples, (b) vx = 1.235 cm/s scanning speed, (c) 1% laser transmission (0.02 mW power) and (d) (Δx, Δy) = (0.33, 0.50 mm) pixel sizes with electronic settings of (a) 300 microseconds time constant, (b) normal dynamic reserve, (c) 24 dB/oct low pass filter slope, and (d) 160 Hz chopping frequency resulted in the highest SNR while maintaining sub‐millimeter spatial resolution. The BaFBr0.85I0.15:Eu2+ storage phosphor dosimeters were linear from 1 to 50 MU and their profiles did not saturate up to 150 MU. The scanner was able to detect lateral displacements of ±1 mm in both the crossline and inline directions and ±0.3 mm beam spread changes that were artificially introduced by varying the incident proton energy. Specific to our proton unit, proton energy changes of ±1 MeV can also be detected indirectly via beam spread measurements. Conclusion Our combined dosimetric system including an in‐hous...

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Experimental study on a helium cryogenic closed loop two-phase thermosyphon with a long heat transport distance

Hu,

Song,

Yang

et al. 2023

Cryogenics

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Excitation Test of Superconducting Magnet in 230-MeV Isochronous Cyclotron for Proton Therapy

Cited by 5 publications

References 1 publication

Technological Developments and Future Perspectives in Particle Therapy: A Topical Review

Technological Developments and Future Perspectives in Particle Therapy: A Topical Review

Development of a storage phosphor imaging system for proton pencil beam spot profile determination

Experimental study on a helium cryogenic closed loop two-phase thermosyphon with a long heat transport distance

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