Executive summary for the 2015 Annual Data Report of the China Kidney Disease Network (CK-NET)

et al. 2020

Seminars in Dialysis

Hemodialysis patients are vulnerable to infectious diseases and frequent receipt of antimicrobial agents. The aim of this study was to describe the prevalence and characteristics of infections and antimicrobials use among hemodialysis outpatients. We utilized the dialysis event surveillance protocol developed by the National Healthcare Safety Network to conduct a prospective multicenter study in Anhui, China. A total of 41 dialysis centers involving 7393 outpatients were included. Fistula was the most common type of vascular access (85.3%), followed by tunneled central line (12.7%), and non‐tunneled central line (1.2%). There were 118 dialysis events with an overall pooled events rate of 1.60 per 100 patient‐months. Intravenous antimicrobial start, positive blood culture, and pus, redness, or increased swelling at the vascular access site were detected at rates of 0.91, 0.23, and 0.46 per 100 patient‐months, respectively. The prevalence of dialysis events was commonly higher in patients with a central line, and lower in patients with a fistula. Hemodialysis outpatients also had the noteworthy risks of nonaccess infections. Older age, female gender, and having a central line were associated with the increased risk of dialysis events. Findings recommend that regular monitoring and improvement strategies are warranted in management of infections among hemodialysis outpatients.

Section: Introductionmentioning

confidence: 99%

Prevalence of infections and antimicrobial use among hemodialysis outpatients: A prospective multicenter study

et al. 2020

Seminars in Dialysis

“…It is characterized by progressive irreversible structural damage and/ or kidney function, ultimately leads to end-stage kidney disease (ESKD), which necessitates treatment with renal replacement therapy such as transplant or dialysis, bring heavy burden to patients and families [2]. According to the report of China Kidney Disease Network (CK-NET), the expenditure of patients with CKD was 23,780 million RMB, accounting for 6.3% of the overall costs [3]. Besides, patients with CKD have an increased risk of mortality with a mortality rate of 2.6%, higher than non-CKD (0.8%), and diabetes mellitus (1.5%) patients in China [3].…”

Section: Introductionmentioning

confidence: 99%

“…According to the report of China Kidney Disease Network (CK-NET), the expenditure of patients with CKD was 23,780 million RMB, accounting for 6.3% of the overall costs [3]. Besides, patients with CKD have an increased risk of mortality with a mortality rate of 2.6%, higher than non-CKD (0.8%), and diabetes mellitus (1.5%) patients in China [3]. Protein-energy wasting (PEW) is a common complication in patients with CKD, with an approximate incidence rate of about < 2% in CKD stages 1-2 and 11-54% in stages 3-5 [4].…”

Section: Introductionmentioning

confidence: 99%

Factors affecting exercise self-efficacy in non-dialysis patients with chronic kidney disease: a cross-sectional study

Liao

et al. 2020

Preprint

Background Chronic kidney disease (CKD) places a continuous burden on public health worldwide, partially attributable to a sedentary lifestyle. Exercise self-efficacy has emerged as a priority for improving physical activity. Here we conduct a survey to determine exercise self-efficacy and factors associated with lower exercise self-efficacy in non-dialysis patients with CKD. Methods A single-center cross-sectional study was performed from October 2018 to April 2019 using the Exercise Self-Efficacy Scale (ESES) to assess exercise self-efficacy. In addition to socio-demographic data, Leicester Uremic Symptom Score (LUSS) was used to evaluated symptom burden for non-dialysis CKD patients. Multiple linear regression was carried out to identify factors that were significantly associated with exercise self-efficacy. Results One hundred and thirty-seven patients participated in the current study. The median score on the ESES was 48.89 (interquartile range: 33.31–64.72). A significantly negative correlation with ESES and symptom burden was observed. The results of multiple linear regression showed a significantly positive association between exercise self-efficacy and higher average monthly income, higher level of daily physical activity. Conclusion The study reveals several important variables that can be taken into consideration when dealing with exercise self-efficacy in non-dialysis CKD patients. our findings reinforce the need to educate patients who are elderly, female, underweight, lower-income, physical inactivity, and higher symptom burden to promote their exercise self-efficacy.

“…patients in 2015. 2 Up to date, whether HD or PD is a better choice for dialysis patients has been debatable. Survival outcomes are important indicators for evaluating the efficacy and effectiveness of these two dialysis modality.…”

Section: Introductionmentioning

confidence: 99%

Effects of dialysis modality choice on survival of end-stage renal disease patients in southern China: A retrospective cohort study

et al. 2020

Preprint

Background Up to date, whether hemodialysis (HD) or peritoneal dialysis (PD) is a better choice for end-stage renal disease (ESRD) patients has been debatable. Few study comparing HD and PD was from China, a large country with the largest number of dialysis patients in the world. Method A retrospective cohort study was conducted on ESRD patients who began renal replace treatment from January 1st, 2012 and December 31st, 2017 in Guangdong Provincial Hospital of Chinese Medicine. We used propensity scoring match model to balance the baseline conditions and Cox's multivariate regression analysis to compare mortality between HD and PD patients, and evaluated the relationship between mortality and various baseline covariates. Results 436 HD patients and 501 PD patients were included and we found that PD patients had better survival than HD patients (The 1-, 3- and 5-year survival rates were 98.1% vs 96.4%, 86.7% vs 83.0%, and 73.4% vs 71.9%), even though the difference was not statistically significant. For younger ESRD patients (<=60 years old), the overall survival of PD was better than that of HD, but HD was associated with lower risk of death in the patients who were older than 70 years of age. This difference was still significant after adjustment for a variety of confounding factors. Female, cardiovascular disease, cholesterol, and HD are risk factors of all-cause mortality in the younger subgroup while PD is risk factor in the older subgroup. Conclusion Younger ESRD patients may be more suitable for PD, and the elderly for HD.