Exercise and Inflammation

Roberts, Llion A.

doi:10.3390/antiox8060155

Cited by 7 publications

(5 citation statements)

References 29 publications

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“…The anti-inflammatory effects of exercise are well understood. In the near future, it is important to identify the effects of exercise from a pathological point of view, and to develop early prognostic markers [2,8,82,[138][139][140][141][142].…”

Section: Discussionmentioning

confidence: 99%

Characterization and Modulation of Systemic Inflammatory Response to Exhaustive Exercise in Relation to Oxidative Stress

et al. 2020

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Exhaustive exercise induces systemic inflammatory responses, which are associated with exercise-induced tissue/organ damage, but the sources and triggers are not fully understood. Herein, the basics of inflammatory mediator cytokines and research findings on the effects of exercise on systemic inflammation are introduced. Subsequently, the association between inflammatory responses and tissue damage is examined in exercised and overloaded skeletal muscle and other internal organs. Furthermore, an overview of the interactions between oxidative stress and inflammatory mediator cytokines is provided. Particularly, the transcriptional regulation of redox signaling and pro-inflammatory cytokines is described, as the activation of the master regulatory factor nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is involved directly or indirectly in controlling pro-inflammatory genes and antioxidant enzymes expression, whilst nuclear factor-kappa B (NF-κB) regulates the pro-inflammatory gene expression. Additionally, preventive countermeasures against the pathogenesis along with the possibility of interventions such as direct and indirect antioxidants and anti-inflammatory agents are described. The aim of this review is to give an overview of studies on the systematic inflammatory responses to exercise, including our own group as well as others. Moreover, the challenges and future directions in understanding the role of exercise and functional foods in relation to inflammation and oxidative stress are discussed.

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Section: Discussionmentioning

confidence: 99%

Characterization and Modulation of Systemic Inflammatory Response to Exhaustive Exercise in Relation to Oxidative Stress

et al. 2020

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“…Exercise training has been known as a lifestyle factor that can maintain and even promote immune function and act like a vaccine against certain diseases/infections through producing physiological stress in the human body which lead to a series of adaptations occurring to overcome these stimuli ( 95 ). The overall health promotion effects of exercise training along with its disease prevention have resulted in the important statement of “Exercise is Medicine” ( 54 , 96 ). These positive adaptations, however, may not be achieved without ingesting some functional foods (e.g., carbohydrate, protein, polyphenols, vitamins, and minerals) and fluids together with suitable timing ( Figure 3 ) in order to help maintain exercise performance and immune function without causing harmful side effects on health ( 97 ).…”

Section: Discussionmentioning

confidence: 99%

Ramadan Fasting During the COVID-19 Pandemic; Observance of Health, Nutrition and Exercise Criteria for Improving the Immune System

et al. 2021

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Fasting is one of the religious rituals of Muslims worldwide who refrain from eating foods and liquids every year during Ramadan. This year (2020), Ramadan is very different from previous years due to the outbreak of a terrible microscopic giant called coronavirus disease 2019 (COVID-19). The pandemic COVID-19 has made Ramadan very important this year because the virus has infected millions of people around the world and killed thousands, especially people with immunodeficiency. In dealing with COVID-19, maintaining good hygiene and supporting the immune system are effective, preventive approaches. Moderate exercise training and proper nutrition are the most important factors to support immune function. Lack of facilities, poor health and many traditions that lead to public community gatherings have made many Islamic countries susceptible to this dangerous virus. In such an unprecedented situation, there are many Muslims who doubt whether they can fast or not. Therefore, the proposal of usable exercise programs and effective nutritional strategies is imperative. In this study, we will look at the proposed health effects of fasting and its impact on the immune system, the effects of Ramadan intermittent fasting on resting values and responses of immunological/antioxidant biomarkers in elite and recreational athletes, together with the important health, nutrition, and exercise advice that fasting people need to follow in the event of a COVID-19 outbreak.

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“…Still, urine-concentrating power was maintained in the IMP-treated group, making them less prone to dehydration [14]. In addition, we proved that eight weeks of IMP administration suppressed the elevation of intestinal fatty acid-binding protein (I-FABP), which is a marker of intestinal injury and inflammatory cytokines after all-out running, and that IMP intake can prevent exercise-induced intestinal damage and inflammation [7,14,90].…”

Section: Prevention Of Exercise-induced Intestinal Injury and Systemic Inflammation By Colostrum And Impmentioning

confidence: 80%

Recent Progress in Applicability of Exercise Immunology and Inflammation Research to Sports Nutrition

Suzuki

2021

Nutrients

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This article focuses on how nutrition may help prevent and/or assist with recovery from the harmful effects of strenuous acute exercise and physical training (decreased immunity, organ injury, inflammation, oxidative stress, and fatigue), with a focus on nutritional supplements. First, the effects of ketogenic diets on metabolism and inflammation are considered. Second, the effects of various supplements on immune function are discussed, including antioxidant defense modulators (vitamin C, sulforaphane, taheebo), and inflammation reducers (colostrum and hyperimmunized milk). Third, how 3-hydroxy-3-methyl butyrate monohydrate (HMB) may offset muscle damage is reviewed. Fourth and finally, the relationship between exercise, nutrition and COVID-19 infection is briefly mentioned. While additional verification of the safety and efficacy of these supplements is still necessary, current evidence suggests that these supplements have potential applications for health promotion and disease prevention among athletes and more diverse populations.

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Exercise and Inflammation

Abstract: Exercise and inflammation induce multi-faceted physiological responses in their own right, let alone when considered together [...]

Cited by 7 publications

References 29 publications

Characterization and Modulation of Systemic Inflammatory Response to Exhaustive Exercise in Relation to Oxidative Stress

Characterization and Modulation of Systemic Inflammatory Response to Exhaustive Exercise in Relation to Oxidative Stress

Ramadan Fasting During the COVID-19 Pandemic; Observance of Health, Nutrition and Exercise Criteria for Improving the Immune System

Recent Progress in Applicability of Exercise Immunology and Inflammation Research to Sports Nutrition

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