Exercise-induced bronchospasm in children and adolescents with allergic rhinitis by treadmill and hyperventilation challenges

Filho, Edil de Albuquerque Rodrigues; Rizzo, José Ângelo; Gonçalves, Adriana Velozo; Correia, Marco Aurélio de Valois; Sarinho, Emanuel Sávio Cavalcanti; Medeiros, Décio

doi:10.1016/j.rmed.2018.04.001

Cited by 8 publications

(5 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In contrast, many previous studies have shown that only the minority (range 0%-27%) of the 8-to 18-year-old children has been able to perform the test at the same 100% of target ventilation rate (Chateaubriand do Nascimento Silva Filho et al, 2015;Jara-Gutierrez et al, 2019;Van der Eycken et al, 2016). Like in our study, the proportion of children reaching minimum 70% of target minute ventilation has been 83%-100% of 8-to 20-year-old children in previous studies (Albuquerque Rodrigues Filho et al, 2018;Chateaubriand do Nascimento Silva Filho et al, 2015;Jara-Gutierrez et al, 2019;Van der Eycken et al, 2016). In addition, among the general adult population, 70% of the target was achieved at a much lower rate (71%) than in our study (Brummel et al, 2009).…”

Section: Discussioncontrasting

confidence: 99%

Cut‐off values to evaluate exercise‐induced asthma in eucapnic voluntary hyperventilation test for children

Burman

Elenius

Lukkarinen

et al. 2020

Clin Physio Funct Imaging

View full text Add to dashboard Cite

Background and Aim The eucapnic voluntary hyperventilation (EVH) testing is a diagnostic tool for diagnostics of exercise‐induced bronchoconstriction; while the testing has become more common among children, data on the test's feasibility among children remain limited. Our aim was to investigate EVH testing feasibility among children, diagnostic testing cut‐off values, and which factors affect testing outcomes. Methods We recruited 134 patients aged 10–16 years with a history of exercise‐induced dyspnoea and 100 healthy control children to undergo 6‐min EVH testing. Testing feasibility was assessed by the children's ability to achieve ≥70% of the target minute ventilation of 30 times forced expiratory volume in 1 s (FEV1). Bronchoconstriction was assessed as a minimum of 8%, 10%, 12%, 15% or 20% fall in FEV1. Patient characteristics were correlated with EVH outcomes. Results Overall, 98% of the children reached ≥70%, 88% reached ≥80%, 79% reached ≥90% and 62% reached ≥100% of target ventilation in EVH testing; of children with a history of exercise‐induced dyspnoea, the decline percentages were as follows: 24% (≥8% fall), 17% (≥10% fall), 10% (≥12% fall), 6% (≥15% fall) and 5% (≥20% fall) in FEV1, compared to 11%, 4%, 3%, 1% and 0% among the healthy controls, respectively. Healthy controls and boys performed testing at higher ventilation rates ( p < .05). Conclusion Eucapnic voluntary hyperventilation testing is feasible among children aged 10–16 years and has diagnostic value in evaluating exercise‐induced dyspnoea among children. A minimum 10% fall in FEV1 is a good diagnostic cut‐off value. Disease status appears to be important covariates.

show abstract

Section: Discussioncontrasting

confidence: 99%

Cut‐off values to evaluate exercise‐induced asthma in eucapnic voluntary hyperventilation test for children

Burman

Elenius

Lukkarinen

et al. 2020

Clin Physio Funct Imaging

View full text Add to dashboard Cite

show abstract

“…[33][34][35][36] The response on initial challenge has a 62% sensitivity of predicting EIB on subsequent challenge. 34,35 Comparative studies of treadmill versus EVH by Filho et al 37,38 with Brazilian children found that these diagnostic techniques were not interchangeable.…”

Section: Diagnosis and Testingmentioning

confidence: 99%

“…Ideally, the original technique used for diagnosis should be reproduced always during the time of intense exercise or training or reproduced with a different technique. [37][38][39] There are various agencies that provide recommendations for diagnostic testing. The World Anti-Doping Agency (WADA), for example, has a list of approved tests and diagnostic criteria detailed in Table II.…”

Section: Diagnosis and Testingmentioning

confidence: 99%

Work Group Report: Perspectives in Diagnosis and Management of Exercise-Induced Bronchoconstriction in Athletes

Greiwe

Cooke²,

Nanda

et al. 2020

The Journal of Allergy and Clinical Immunology: In Practice

View full text Add to dashboard Cite

AAAAI Position Statements, Work Group Reports, and Systematic Reviews are not to be considered to reflect current AAAAI standards or policy after five years from the date of publication. The statement below is not to be construed as dictating an exclusive course of action nor is it intended to replace the medical judgment of healthcare professionals. The unique circumstances of individual patients and environments are to be taken into account in any diagnosis and treatment plan. The statement reflects clinical and scientific advances as of the date of publication and is subject to change.For reference only.Exercise-induced bronchoconstriction, otherwise known as exercise-induced bronchoconstriction with asthma or without asthma, is an acute airway narrowing that occurs as a result of exercise and can occur in patients with asthma. A panel of members from the American Academy of Allergy, Asthma & Immunology Sports, Exercise, & Fitness Committee reviewed the diagnosis and management of exercise-induced bronchoconstriction in athletes of all skill levels including recreational athletes, high school and college athletes, and professional athletes. A special emphasis was placed on the recommendations and regulations set forth by professional athletic organizations after a detailed review of their collective bargaining agreements, substance abuse policies, antidoping program manuals, and the World Anti-Doping Agency antidoping code. The recommendations in this review are based on currently available evidence in addition to providing guidance for athletes of all skill levels as well as their treating physicians to better understand which pharmaceutical and

show abstract

“…Exercise-induced rhinitis is frequent, especially in outdoor sports such as winter athletes [ 23 ]. About 20–40% of children with rhinitis have EIB, particularly those with persistent untreated signs and symptoms [ 23 , 24 ]. On this basis, the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines recommend screening every subject with rhinitis, including athletes, for asthmatic clinical manifestations [ 25 ].…”

Section: Atopy and Eibmentioning

confidence: 99%

“…These processes include alterations in airway osmolarity, epithelial damage, airway inflammation, and activation of nerve cells. This initial hypothesis is called the osmotic hypothesis: exercise increases ventilation, leading to mouth breathing, cooling and dehydration of the airway mucosa [ 24 ]. As a result of dehydration, liquid layer osmolarity increases, causing the release of mediators, including prostaglandins, leukotrienes, and histamine, leading to smooth muscle contraction and altering vascular permeability [ 37 ].…”

Section: Underlying Mechanisms Of Eia and Eibmentioning

confidence: 99%

Exercise-induced bronchoconstriction, allergy and sports in children

Klain,

Giovannini,

Pecoraro

et al. 2024

Ital J Pediatr

View full text Add to dashboard Cite

Exercise-induced bronchoconstriction (EIB) is characterized by the narrowing of airways during or after physical activity, leading to symptoms such as wheezing, coughing, and shortness of breath. Distinguishing between EIB and exercise-induced asthma (EIA) is essential, given their divergent therapeutic and prognostic considerations. EIB has been increasingly recognized as a significant concern in pediatric athletes. Moreover, studies indicate a noteworthy prevalence of EIB in children with atopic predispositions, unveiling a potential link between allergic sensitivities and exercise-induced respiratory symptoms, underpinned by an inflammatory reaction caused by mechanical, environmental, and genetic factors. Holistic management of EIB in children necessitates a correct diagnosis and a combination of pharmacological and non-pharmacological interventions. This review delves into the latest evidence concerning EIB in the pediatric population, exploring its associations with atopy and sports, and emphasizing the appropriate diagnostic and therapeutic approaches by highlighting various clinical scenarios.

show abstract

Exercise-induced bronchospasm in children and adolescents with allergic rhinitis by treadmill and hyperventilation challenges

Cited by 8 publications

References 32 publications

Cut‐off values to evaluate exercise‐induced asthma in eucapnic voluntary hyperventilation test for children

Cut‐off values to evaluate exercise‐induced asthma in eucapnic voluntary hyperventilation test for children

Work Group Report: Perspectives in Diagnosis and Management of Exercise-Induced Bronchoconstriction in Athletes

Exercise-induced bronchoconstriction, allergy and sports in children

Contact Info

Product

Resources

About