Exercise training in patients after kidney transplantation

Smet, Stefan De; Craenenbroeck, Amaryllis H. Van

doi:10.1093/ckj/sfab022

Cited by 29 publications

(22 citation statements)

References 89 publications

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“…There is now emerging evidence that a sedentary lifestyle can be associated with an increased risk of cardiovascular events, a major cause of morbidity and mortality after KT [ 82 , 83 , 84 , 85 ]. On the other hand, regular exercise and physical activity may reduce the burden of cardiovascular risk factors and improve the perceived health status and QoL.…”

Section: Discussionmentioning

confidence: 99%

Physical Inactivity: A Modifiable Risk Factor for Morbidity and Mortality in Kidney Transplantation

Ponticelli

Favi

2021

JPM

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In patients with chronic kidney disease, sedentary behavior is widely recognized as a significant risk factor for cardiovascular disease, diabetes, obesity, osteoporosis, cancer, and depression. Nevertheless, the real impact of physical inactivity on the health of kidney transplant (KT) recipients remains uncertain. Over the last decade, there has been a renewed interest in exploring the effects of regular physical exercise on transplant-related outcomes. There is now mounting evidence that physical activity may reduce the burden of cardiovascular risk factors, preserve allograft function, minimize immunosuppression requirement, and ameliorate the quality of life of KT recipients. Many positive feedbacks can be detected in the early stages of the interventions and with a minimal exercise load. Despite these encouraging results, the perceived role of physical activity in the management of KT candidates and recipients is often underrated. The majority of trials on exercise training are small, relatively short, and focused on surrogate outcomes. While waiting for larger studies with longer follow-up, these statistical limitations should not discourage patients and doctors from initiating exercise and progressively increasing intensity and duration. This narrative review summarizes current knowledge about the deleterious effects of physical inactivity after KT. The benefits of regular physical exercise are also outlined.

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Section: Discussionmentioning

confidence: 99%

Physical Inactivity: A Modifiable Risk Factor for Morbidity and Mortality in Kidney Transplantation

Ponticelli

Favi

2021

JPM

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“…Especially developing adapted interventions and use of specific implementation strategies can support to reach these patients and to get and keep them more physically active. RCTs show a bias towards inclusion of more physically active patients or patients willing to engage in physical activity [ 62 , 63 ]. Also in Transplantoux this has been the case, resulting in a selection bias.…”

Section: Discussionmentioning

confidence: 99%

Patient-reported outcomes evaluation and assessment of facilitators and barriers to physical activity in the Transplantoux aerobic exercise intervention

et al. 2022

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Background Transplantoux’s MVT exercise intervention prepares organ transplant recipients to cycle or hike up France’s Mont Ventoux. We aimed to assess (i) MVT’s effects on patient-reported outcomes (PROs) and (ii) perceived barriers and facilitators to physical activity. Methods Using a hybrid design, a convenience sample of transplant recipients participating in MVT (n = 47 cycling (TxCYC); n = 18 hiking (TxHIK)), matched control transplant recipients (TxCON, n = 213), and healthy MVT participants (HCON, n = 91) completed surveys to assess physical activity (IPAQ), health-related quality of life (HRQOL; SF-36 and EuroQol VAS), mental health (GHQ-12), and depressive symptomatology, anxiety, and stress (DASS-21) at baseline, then after 3, 6 (Mont Ventoux climb), 9, and 12 months. TxCYC and TxHIK participated in a 6-month intervention of individualized home-based cycling/hiking exercise and a series of supervised group training sessions. Barriers and facilitators to physical activity (Barriers and Motivators Questionnaire) were measured at 12 months. Results Regarding PROs, except for reducing TxHIK stress levels, MVT induced no substantial intervention effects. For both TxCYC and TxHIK, between-group comparisons at baseline showed that physical activity, HRQOL, mental health, depressive symptomatology and stress were similar to those of HCON. In contrast, compared to TxCYC, TxHIK, and HCON, physical activity, HRQOL and mental health were lower in TxCON. TxCON also reported greater barriers, lower facilitators, and different priority rankings concerning physical activity barriers and facilitators. Conclusion Barely any of the PROs assessed in the present study responded to Transplantoux’s MVT exercise intervention. TxCON reported distinct and unfavorable profiles regarding PROs and barriers and facilitators to physical activity. These findings can assist tailored physical activity intervention development. Trial registration Clinical trial notation: The study was approved by the University Hospitals Leuven’s Institutional Review Board (B322201523602).

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“…The results demonstrated that psychomotor activity could provide an effective support tool for school learning. References ESERCIZIO, PREVENZIONE E TERAPIA 3 31 Interrelationship among thigh intermuscular adipose tissue, cross-sectional area, muscle strength and functional mobility in older subjects…”

Section: Discussionmentioning

confidence: 99%

XII National Congress SISMES Padua, 8–10 October, 2021

2021

Sport Sci Health

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Exercise training in patients after kidney transplantation

Cited by 29 publications

References 89 publications

Physical Inactivity: A Modifiable Risk Factor for Morbidity and Mortality in Kidney Transplantation

Physical Inactivity: A Modifiable Risk Factor for Morbidity and Mortality in Kidney Transplantation

Patient-reported outcomes evaluation and assessment of facilitators and barriers to physical activity in the Transplantoux aerobic exercise intervention

XII National Congress SISMES Padua, 8–10 October, 2021

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