This paper is devoted to the study of a nonlinear wave equation with initial conditions and nonlocal boundary conditions of 2N-point type, which connect the values of an unknown function u(x,t) at x = 1, x = 0, x = i (t), and x = i (t), where 0 < 1 (t) < 2 (t) < … < N−1 (t) < 1, 0 < 1 (t) < 2 (t) < … < N−1 (t) < 1, for all t ≥ 0. First, we prove local existence of a unique weak solution by using density arguments and applying the Banach's contraction principle. Next, under the suitable conditions, we show that the problem considered has a unique global solution u(t) with energy decaying exponentially as t → +∞. Finally, we present numerical results.