Exon Skipping and Myoblast Transplantation: Single or Combined Potential Options for Treatment of Duchenne Muscular Dystrophy

Iannitti, Tommaso; Lodi, D.; Sblendorio, Valeriana; Rottigni, Valentina; Palmieri, Beniamino

doi:10.5772/30656

Muscular Dystrophy 2012

DOI: 10.5772/30656

|View full text |Cite

Exon Skipping and Myoblast Transplantation: Single or Combined Potential Options for Treatment of Duchenne Muscular Dystrophy

Tommaso Iannitti¹,

D. Lodi²,

Valeriana Sblendorio³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2014

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 138 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Phosphorothioate Oligonucleotides: Effectiveness and Toxicity

Iannitti¹,

Morales‐Medina

Palmieri

2014

CDT

View full text Add to dashboard Cite

Phosphorothioate oligonucleotide transient activation of the complement cascade represents the most evident toxicological response, as showed by in vivo studies. It is also known that many of these compounds induce a prolongation of activated partial thromboplastin time, a reaction which is often highly transient and proportional to the oligonucleotide plasma concentrations, making that effect clinically insignificant for the current treatment regimens. In summary, current evidence shows limited untoward effects and reversibility of the damage induced, at least for some of those compounds, with promising effectiveness for treatment of various pathologies.

show abstract

Phosphorothioate Oligonucleotides: Effectiveness and Toxicity

Iannitti¹,

Morales‐Medina

Palmieri

2014

CDT

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Exon Skipping and Myoblast Transplantation: Single or Combined Potential Options for Treatment of Duchenne Muscular Dystrophy

Cited by 1 publication

References 138 publications

Phosphorothioate Oligonucleotides: Effectiveness and Toxicity

Phosphorothioate Oligonucleotides: Effectiveness and Toxicity

Contact Info

Product

Resources

About