Expeditious Microwave-Assisted Thionation with the System PSCl₃/H₂O/Et₃N under Solvent-Free Condition

Abstract

A novel thionation protocol for carbonyl compounds, with the system PSCl3/H2O/Et3N has been discovered. Clean, rapid, and efficient synthesis of a variety of thiocarbonyl compounds such as thioamides, thiolactams, thioketones, thioxanthones, and thioacridone can be achieved through this simple and convenient method under solventless condition with microwave irradiation.

Generation, Reactivity and Uses of Sulfines in Organic Synthesis

“…[27][28][29] Due to this ease of access to thiocarbonyl compounds, oxidation of these is a widely used route to sulfines. [27][28][29] Due to this ease of access to thiocarbonyl compounds, oxidation of these is a widely used route to sulfines.…”

“…The conversion of ketones and aldehydes into thiocarbonyl compounds is a simple, one-pot, one-step reaction often carried out under microwave irradiation and resulting in high yields. [27][28][29] Due to this ease of access to thiocarbonyl compounds, oxidation of these is a widely used route to sulfines. The oxidation of thiocarbonyl compounds to sulfines has been reported using m-CPBA, [6] and monoperphthalic acid.…”

On the Formation and 1H NMR-spectroscopic Characterization of N,N-Diaryl-substituted Formamide Chlorides

“….93 a [9,10] 7.92 b [11] 8.02 c [25] 7.95 d [25] 10.10 a [9,10] 11.08 b [11] 9.21 d [15] 9.21 d [16] 10.56 d [17] 10.62 d [18] 10.32 d [19] 7.40 d [20] b 8.48 [21] 8.53 c [25] 8.48 d [25] 9.51 a [9] 9.36 / 9.46 b [14] 9.64 e [12] 11.17 d [18] 11.22 d [22] 8.10 d [13] c 8.55 d [23] 8.64 d [24] 7.60 d , f 10.0 d [16] 8.67 d [20] 11.75 d [16] 8.18 d [25] …”

Microwave Promoted Regeneration of Carbonyl Compounds from Oximes Using N, N‐Dichloro Poly(Styrene‐co‐divinylbenzene)Sulphonamide Resin

“…Heterogenised reagents [26][27][28] has evinced the attention of researchers because of their handling ease, lower toxicity, non explosive and malodorous nature. Another important motive of supported reagents is facile isolation of the pure product than their solution phase equivalents.…”