Experience of Using a Cellular Energy Protector in the Complex Treatment of Acute Kidney Injury in an Adolescent With Metamizole Poisoning

Abstract

Every year, 1,700–1,850 pediatric patients apply to the Department of Toxicology of Filatov Children's City Clinical Hospital for specialized medical care. More than 56% of hospitalizations are caused by medicinal poisoning. One of the serious complications of drug intoxication is acute kidney injury (AKI). The incidence of AKI in acute chemical poisoning in childhood is from 10 to 57,6% according to various authors, therefore, the issues of effective treatment of AKI in the medical practice of doctor of any specialty are extremely relevant. The article presents the case of conservative treatment of AKI stage 3 according to the KDIGO classification in a teenager with metamizole poisoning, including inclusion of «Cytoflavin» cellular energy protector as a part of complex therapy. As a result of the treatment, the level of proteinuria and azotemia in the child has decreased. The rate of tuber filtration has increased from 20,0 to 62,4 ml/min/1,73 m2. Thus, the use of a cellular energy protector contributed to effective restoration of renal function.