Fast technologies for numerical simulation of high-speed flows in ducts, developed in TsAGI, are described. The examples are presented of the application of experimental data, obtained at T-131 wind tunnel, for validation of the developed numerical technologies: 1) validation of 2.5D and 3D calculations of flow in the elliptic combustor with hydrogen supersonic combustion that was studied within HEXAFLY-INT international project; 2) validation of 2D and 2.5D calculations of flow in high-speed model combustor duct with step-like expansion. Preparation of new series of experiments, oriented on validation of turbulent combustion models, is described.