Experience with a comprehensive university hospital-based infertility program in Nigeria

Orhue, Aae; Aziken, ME

doi:10.1016/j.ijgo.2007.09.034

Cited by 27 publications

(31 citation statements)

References 11 publications

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“…Conventional infertility treatments are not always effective, however, as shown in a report from the University of Benin Teaching Hospital (UBTH) [6]. A study of the first 10 years of a 21-year infertility program at UBTH, implemented with the help of the WHO and in which only conventional methods were used, revealed that no pregnancies occurred for 60% of almost 2000 couples treated during these years.…”

Section: Introductionmentioning

confidence: 47%

“…Since the Unit was a WHO collaborating center in human reproduction, it was visited from time to time by resource persons from the WHO headquarters in Geneva. These persons supervised and streamlined the program during the 5 years of the LID grant duration and a report on the first 10 years of the experiment was published by Orhue et al [6]. The results revealed that, in spite of all the concerted efforts to treat their infertility, about 60% of the couples did not achieve pregnancy by the conventional methods practiced.…”

Section: Discussionmentioning

confidence: 99%

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In vitro fertilization at a public hospital in Nigeria

Orhue

Aziken

Osemwenkha

et al. 2012

Intl J Gynecology & Obste

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Section: Introductionmentioning

confidence: 47%

Section: Discussionmentioning

confidence: 99%

In vitro fertilization at a public hospital in Nigeria

Orhue

Aziken

Osemwenkha

et al. 2012

Intl J Gynecology & Obste

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“…A study in Nigeria found a cumulative incidence of pregnancy of 40% in 1948 couples followed up for a maximum of 10 years. 8 In Ghana, a cumulative incidence of spontaneous pregnancies of 12% was reported among 1000 infertile patients followed up for 18 months. 6 Rwanda is a poor, overpopulated and landlocked country in Central Africa and the Great Lakes region.…”

Section: Introductionmentioning

confidence: 99%

Results of infertility investigations and follow-up among 312 infertile women and their partners in Kigali, Rwanda

et al. 2011

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The objectives of this study were to assess the outcome of infertility investigations and an 18-month follow-up of 312 infertile women and their partners in Rwanda. Between November 2007 and May 2009, an infertility research clinic was opened. Infertile couples received basic infertility investigations, the available treatment was provided and couples were followed up over an 18-month period. The infertility remained unexplained in 3%, was due to a female factor in 31%, due to a male factor in 16% or due to a combination of male and female causes in 50% of fully investigated couples (n = 224). A tubal factor was found in 69% of women, a male factor in 64% of men. Predictors for tubal infertility in women included a history of high-risk sexual behaviour, HIV infection and a history of sexually transmitted infection (STI) symptoms in the male partner. After 12-18 months of follow-up, 40 pregnancies (16%) had occurred in 244 women. Our study shows high rates of tubal and male factor infertility in Rwanda. Pregnancy rates were low after conventional therapy. In order to provide effective and affordable treatment for infertility in resource-poor countries the development of low-cost assisted reproductive technologies are needed.

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“…The aetiological factors include tuboperitoneal diseases, anovulation, uterine lesions and semen fluid abnormalities (Adeyemi et al, 2009;Obuna et al, 2012;Orhue and Aziken, 2008).…”

Section: Introductionmentioning

confidence: 95%

“…Infertility, which refers to the inability of a couple to conceive after one year of regular unprotected sexual intercourse, is the commonest indication for outpatient gynaecological consultation in Nigeria (Adeyemi et al, 2009;Obuna et al, 2012;Orhue and Aziken, 2008;Ikechebelu, 2005;Karshima et al, 2014). The aetiological factors include tuboperitoneal diseases, anovulation, uterine lesions and semen fluid abnormalities (Adeyemi et al, 2009;Obuna et al, 2012;Orhue and Aziken, 2008).…”

Section: Introductionmentioning

confidence: 99%

Abnormal laparoscopy findings among infertile women attending a mission hospital in Nigeria

Ugboaja¹,

Oguejiofor²,

Ogelle³

2017

Int. J. Med. Med. Sci.

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This research aims to study the findings from diagnostic laparoscopy among infertile women managed in a secondary healthcare center in Nigeria. This is a prospective study of eighty infertile women who had diagnostic laparoscopy in a secondary healthcare facility in Nigeria. The age range of the women was 24 to 45 years with most of them belonging to the parity group of 0 to 1 (90.0%; n=0.72). Primary infertility accounted for 43(53.8%) of cases, whereas the mean duration of infertility was 4.3+/-2.4 years. Fifty-seven (71.3%) of the women had abnormal findings at laparoscopy. This comprised mainly of tubal pathologies (63.8%, n=51), pelvic adhesions (33.8%, n=27) and uterine fibroids (31.3%, n=25). Tubal occlusion was found in 39(48.8%) of the women, compromised bilateral tubal occlusion in 12(15.0%) and unilateral tubal occlusion in 27(33.8%) of cases. Distal tubal occlusion accounted for 24(30.0%) while proximal tubal occlusion was seen in 15(18.8%) of cases. While there were 21(26.3%) cases of polycystic ovaries, there was no significant difference in prevalence of abnormal laparoscopy (p=0.8), tubal pathology (p=0.5) and tubal occlusion (p=0.18) with respect to the type of infertility. There was a high rate of abnormal laparoscopy findings among the studied women which were mainly tubal occlusion and pelvic adhesions. These findings indicate the need to incorporate laparoscopy in the initial evaluation of all infertility cases in our environment.

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Experience with a comprehensive university hospital-based infertility program in Nigeria

Abstract: Pregnancy outcome was relatively poor because conventional treatments did not cure the most prevalent causes of infertility, and assisted reproductive technology is therefore advocated.

Cited by 27 publications

References 11 publications

In vitro fertilization at a public hospital in Nigeria

In vitro fertilization at a public hospital in Nigeria

Results of infertility investigations and follow-up among 312 infertile women and their partners in Kigali, Rwanda

Abnormal laparoscopy findings among infertile women attending a mission hospital in Nigeria

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