Experimental Acute Pancreatitis in Dogs

Treatment of Acute Pancreatitis: An Attempted Historical Review

“…Pancreatic ascites fluid given intravenously led to a sharp decrease in blood pressure in healthy dogs [33,34]. The reason for this effect was unknown, but it was proposed to be partly due to histamine [35,36]. In a similar experiment, ascites fluid given intraperitoneally also led to a decrease in blood pressure [37].…”

Clinical pancreatology I: Pancreatic medical history

“…Pancreatic ascites fluid given intravenously led to a sharp decrease in blood pressure in healthy dogs[2829]. The reason for this effect was unknown, but it was proposed to be partly due to histamine[3031]. In a similar experiment, ascites fluid given intraperitoneally also led to a decrease in blood pressure[32].…”