The current paper presents a computational fluid dynamics (CFD) flow behaviour and losses analysis of twin-entry radial turbines in terms of its Mass Flow Ratio ( MFR, the ratio between the flow passing through one of its intake ports and its total mass flow), focusing on the mixing phenomena in the unequal admission conditions cases. The CFD simulations are first validated with experimental data. Then, the losses mechanisms are analysed and quantified in the different parts of the twin-entry turbine in terms of the MFR value. A sudden expansion is found at the junction of both branches in the interspace between volutes and rotor for unequal and partial admission cases. Tracking the flow coming from each of the turbine intake ports, it has been observed that both flow branches do not fully mix with each other within the rotor. Another source of losses has been identified in the contact between both flow branches due to their momentum exchange that depends on the difference between both flow branches velocities. These losses have not been considered before, and they should be included in mean line loss-based models for twin-entry turbine since they are very significant for unequal admission conditions.