Experimental Chronic Gastric Ulcer

Abstract

muscular injections repeated once or twice at long intervals (eight weeks), in those cases in which the tonic, stimulating and alterative effect is desired, as well as a certain specific action ; small, oft-repeated (week or ten days) doses, intramuscularly, over a long period of time, in those chronic diseases in which a purely tonic, stimulating and alterative effect is desired.1198 Bushwick Avenue.

Tabes Dorsalis and Perforated Duodenal Ulcer

“…In addition Crohn and Wilensky (1917) called attention to the frequent disturbance of gastric motility associated with gastric crises. That delayed emptying predisposes to ulcer and causes retarded healing in experimental dogs has been shown by Friedman and Hamburger (1914).…”

Bile induced chronic gastric ulcer in swine

“…There are 2 theories of the pathogenesis of gastric ulcer, that of gastric retention and that of duodenogastric reflux. The association between gastric ulcer and gastric retention has been recognized for many years [1][2][3]. Dragstedt suggested [4,5] that gastric retention stimulated the antrum to release gastrin, resulting in increased acid secretion and consequent ulceration.…”