Experimental determination of proton-induced cross-sections on natural zirconium

Khandaker, Mayeen Uddin; Kim, K.; Lee, M.W.; Kim, K.S.; Kim, G.N.; Cho, Y.S.; Lee, Y.O.

doi:10.1016/j.apradiso.2009.02.031

Cited by 22 publications

(7 citation statements)

References 16 publications

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“…The experiment for nat Nd(p,x) reactions was performed by a stacked-foil activation technique using the incident proton energy of 45 MeV provided by the MC-50 cyclotron of KIRAMS [16,17] details of the experimental setup are described elsewhere [18][19][20]. The natural Nd metallic foils made by Alfa Aesar were used for the experiment.…”

Section: Methodsmentioning

confidence: 99%

Production cross sections of products in the proton induced reactions on natNd in the energy region up to 45 MeV

Yang

Kim

Tao

et al. 2015

Nuclear Instruments and Methods in Physics Research Section B:

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Section: Methodsmentioning

confidence: 99%

Production cross sections of products in the proton induced reactions on natNd in the energy region up to 45 MeV

Yang

Kim

Tao

et al. 2015

Nuclear Instruments and Methods in Physics Research Section B:

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“…Recent advancements in the medical sciences and multiple applications of radioisotopes in research and development have widened the interdisciplinary fields. Physicists, chemists, physicians, industrialists, and agriculturalists are getting benefits of radioisotopes by applying them in the respective fields of research [1][2][3].…”

Section: Introductionmentioning

confidence: 99%

Measurement of excitation functions in alpha-induced reactions on yttrium

Shahid

Kim

Naik

et al. 2015

Nuclear Instruments and Methods in Physics Research Section B:

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Y(a,x) reactions MC-50 cyclotron Stacked-foil activation technique Excitation functionOff line c-ray spectrometry a b s t r a c tThe excitation functions of 89g,m,90,91m,92m Nb, 88,89 Zr, and 87g,m,88,90m,91m Y from alpha-induced reactions on 89 Y were measured from their respective threshold to 45 MeV by using a stacked-foil activation technique at the MC-50 cyclotron of the Korean Institute of Radiological and Medical Sciences. The results were compared with the earlier reported data as well as with the theoretical values obtained from the TENDL-2013 library based on the TALYS1.6 code. Our measurements in the energy region from the threshold energy to 45 MeV are in general good agreement with the other experimental data and calculated results. The integral yields for thick target of the produced radionuclides were also deduced from their measured cross sections and the stopping power of 89 Y. The measured excitation functions find importance in various practical applications including nuclear medicine and improvement of nuclear model calculations.

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“…Since then, many groups have repeatedly investigated this reaction for production, but no new cross-section measurement has been done. For the nat Rb( 3 He,xn) 86 Y reaction, also cross-sections were measured only once [15], but for the nat Zr(p,x) 86 Y reaction, a few new measurements have been reported over the last few years [17,18,19,20]. Very recently, cross-section data for a few reactions have been evaluated using rigorous nuclear model calculations, and recommended data have been presented [21].…”

Section: Nuclear Datamentioning

confidence: 99%

“…Similarly, in the nat Zr(p,x) 86 Y process, the level of the 87 Y impurity formed via the 90 Zr(p,α) 87 Y reaction could be minimized if the incident protons have energies >25 MeV where the 90 Zr(p,αn) 86 Y reaction is favored. We therefore show the integral yields of 86 Y in Figure 2 also from those reactions, taking the data for the nat Rb( 3 He,xn) 86 Y process from [15] and those for the nat Zr(p,x) 86 Y process from [17,18,19,20,21]. It should be mentioned that in the case of the latter two reactions, the use of highly enriched 85 Rb and 9 0 Zr as targets would increase the 86 Y yield by about 25 and 100%, respectively, but it would not alter the radioactive impurity level to any significant extent, provided the energy ranges used in the targets are the same as given in Table 2 (see below).…”

Section: Nuclear Datamentioning

confidence: 99%

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The Beginning and Development of the Theranostic Approach in Nuclear Medicine, as Exemplified by the Radionuclide Pair 86Y and 90Y

2017

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In the context of radiopharmacy and molecular imaging, the concept of theranostics entails a therapy-accompanying diagnosis with the aim of a patient-specific treatment. Using the adequate diagnostic radiopharmaceutical, the disease and the state of the disease are verified for an individual patient. The other way around, it verifies that the radiopharmaceutical in hand represents a target-specific and selective molecule: the “best one” for that individual patient. Transforming diagnostic imaging into quantitative dosimetric information, the optimum radioactivity (expressed in maximum radiation dose to the target tissue and tolerable dose to healthy organs) of the adequate radiotherapeutical is applied to that individual patient. This theranostic approach in nuclear medicine is traced back to the first use of the radionuclide pair 86Y/90Y, which allowed a combination of PET and internal radiotherapy. Whereas the β-emitting therapeutic radionuclide 90Y (t½ = 2.7 d) had been available for a long time via the 90Sr/90Y generator system, the β+ emitter 86Y (t½ = 14.7 h) had to be developed for medical application. A brief outline of the various aspects of radiochemical and nuclear development work (nuclear data, cyclotron irradiation, chemical processing, quality control, etc.) is given. In parallel, the paper discusses the methodology introduced to quantify molecular imaging of 86Y-labelled compounds in terms of multiple and long-term PET recordings. It highlights the ultimate goal of radiotheranostics, namely to extract the radiation dose of the analogue 90Y-labelled compound in terms of mGy or mSv per MBq 90Y injected. Finally, the current and possible future development of theranostic approaches based on different PET and therapy nuclides is discussed.

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Experimental determination of proton-induced cross-sections on natural zirconium

Cited by 22 publications

References 16 publications

Production cross sections of products in the proton induced reactions on natNd in the energy region up to 45 MeV

Production cross sections of products in the proton induced reactions on natNd in the energy region up to 45 MeV

Measurement of excitation functions in alpha-induced reactions on yttrium

The Beginning and Development of the Theranostic Approach in Nuclear Medicine, as Exemplified by the Radionuclide Pair 86Y and 90Y

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