Experimental Heterotopic Ossification

Bridges, J. B.

doi:10.1016/s0074-7696(08)62733-3

Cited by 31 publications

(9 citation statements)

References 44 publications

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“…Aberrant deposits of bone have been found in almost every organ of the human body (Keith 1927) and heterotopic bone can be produced experimentally in a number of ways, notably in relationtotissuesoftheurinarytract (Bridges 1959). Bone will grow into porous materials put adjacent to the skeleton, where repair is taking place, but spontaneous bone growth is not usually associated with implants of foreign materials, solid or porous, although Selye et al (1960) have described bone formation in glass cylinders in the skin of rats.…”

Section: Discussionmentioning

confidence: 99%

Heterotopic Bone Formation in a Synthetic Sponge

Winter

1970

Proceedings of the Royal Society of Medicine

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Section: Discussionmentioning

confidence: 99%

Heterotopic Bone Formation in a Synthetic Sponge

Winter

1970

Proceedings of the Royal Society of Medicine

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“…On the other hand, extraosseous implants of sclera beneath the capsule of the kidney in rabbits (TtirnbuU, Freeman & Melcher 1976) led to bone formation in some instances. However, it is well known that tbe kidney undergoes ossification following damage to its blood supply (Bridges 1959), and such results should be interpreted with caution.…”

Section: Discussionmentioning

confidence: 99%

The effect of scleraf grafts in osseous defects in rabbits

Beveridge

Fox

Browne

1977

J of Periodontal Research

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Scleral grafts were implanted into bony cavities in the tibiae of 8 rabbits for periods of two to six weeks. By four weeks, control unfilled cavities were full of woven bone, which had been remodelled into mature compact bone by six weeks. Healing of cavities filled with scleral allografts was delayed and they were BOt filled with woven bone until six weeks. There was no evidence of osteogenetic induction of sclera. Human heterografts caused marked rejection responses.

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“…Kauffman (1924) recorded 2 cases and Kearns (1934), in a discussion on heterotopic bone, mentioned an additional case. Bridges (1959) concluded that heterotopic ossification may occur in almost any part of the connective tissue in the body but no definite aetiological factor is known. Michaud (1908), Pozzi and Bender (191 2 ) , Strong ( 19 14), Lehmacher ( 19 1 6 ) , Asami ( 19202, Reichelt (1928) and Kulka ( 1942) have all reported undoubted instances of heterotopic bone formation in the fallopian tubes, Meyer (1930), Brocq et al (1948), Flamand (1950 and Gerbie et al (1958) in the endometrium.…”

Section: Discussion and Review Of The Literaturementioning

confidence: 99%