2012
DOI: 10.1128/aem.01169-12
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Experimental Inoculation of Male Rats with Coxiella burnetii: Successful Infection but No Transmission to Cage Mates

Abstract: dBeginning in 2007, the largest human Q fever outbreak ever described occurred in the Netherlands. Dairy goats from intensive farms were identified as the source, amplifying Coxiella burnetii during gestation and shedding large quantities during abortions. It has been postulated that wild rodents are reservoir hosts from which C. burnetii can be transmitted to domestic animals and humans. However, little is known about the infection dynamics of C. burnetii in wild rodents. The aim of this study was to investig… Show more

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Cited by 4 publications
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“…C. burnetii is predominantly found in the urine, feces, amniotic fluid, and other excretions of infected animals. C. burnetii has a long environmental persistence, can form aerosols under certain conditions, and can spread Q fever over long distances via wind [5,6]. Inhalation is the primary route of human infection, leading to pulmonary disease, although systemic infections can arise via lymphatic and hematopoiesis spread.…”
Section: Discussionmentioning
confidence: 99%
“…C. burnetii is predominantly found in the urine, feces, amniotic fluid, and other excretions of infected animals. C. burnetii has a long environmental persistence, can form aerosols under certain conditions, and can spread Q fever over long distances via wind [5,6]. Inhalation is the primary route of human infection, leading to pulmonary disease, although systemic infections can arise via lymphatic and hematopoiesis spread.…”
Section: Discussionmentioning
confidence: 99%